Stock-Based Compensation - Compensation Expense (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2022	Sep. 30, 2021	Sep. 30, 2022	Sep. 30, 2021
Options to purchase common stock
Stock based compensation expense
Options granted (in shares)			265,000
Stock-based compensation expense	$ 40,338	$ 26,459	$ 116,398	$ 84,797
Unrecognized compensation expense	304,900		$ 304,900
Unrecognized compensation expense, weighted average period of recognition			2 years 8 months 12 days
Options to purchase common stock | Cost of revenues
Stock based compensation expense
Stock-based compensation expense	2,124	1,262	$ 5,903	3,246
Options to purchase common stock | Research and development
Stock based compensation expense
Stock-based compensation expense	13,469	6,652	35,343	17,142
Options to purchase common stock | Selling, general and administrative
Stock based compensation expense
Stock-based compensation expense	24,745	18,545	75,152	64,409
Employee stock options
Stock based compensation expense
Stock-based compensation expense	39,620	25,982	114,514	83,645
Employee stock options | Cost of revenues
Stock based compensation expense
Stock-based compensation expense	2,124	1,262	5,903	3,246
Employee stock options | Research and development
Stock based compensation expense
Stock-based compensation expense	12,972	6,242	33,911	16,168
Employee stock options | Selling, general and administrative
Stock based compensation expense
Stock-based compensation expense	24,524	18,478	$ 74,700	64,231
Non-employee stock options
Stock based compensation expense
Options granted (in shares)			25,865
Stock-based compensation expense	718	477	$ 1,884	1,152
Non-employee stock options | Research and development
Stock based compensation expense
Stock-based compensation expense	497	410	1,432	974
Non-employee stock options | Selling, general and administrative
Stock based compensation expense
Stock-based compensation expense	$ 221	$ 67	$ 452	$ 178