Leases (Details) $ in Thousands	1 Months Ended	3 Months Ended		6 Months Ended
	Sep. 30, 2021 USD ($) ft²	Jun. 30, 2022 USD ($) ft²	Jun. 30, 2021 USD ($)	Jun. 30, 2022 USD ($) ft² item lease	Jun. 30, 2021 USD ($)	Dec. 31, 2021 USD ($)
Lessee, Lease, Description [Line Items]
Operating lease liabilities, current portion included in other accrued liabilities | $		$ 5,636		$ 5,636		$ 5,752
Operating lease liabilities, long-term portion | $		65,417		65,417		61,036
Operating lease liabilities | $		$ 71,053		71,053		$ 66,788
Noncash investing activities related to right-of-use assets | $				$ 7,500	$ 30,100
Weighted average remaining lease term		4 years 10 months 20 days		4 years 10 months 20 days
Weighted average discount rate (as a percent)		6.20%		6.20%
Lease expense | $		$ 3,300	$ 2,700	$ 6,500	5,400
Operating lease payments | $		$ 2,800	$ 2,500	$ 5,528	$ 4,992
Austin TX, Long-term Lease
Lessee, Lease, Description [Line Items]
Office space (area)		94,000		94,000
Number of office space locations | lease				2
Term of lease		132 months		132 months
First Expansion Premises
Lessee, Lease, Description [Line Items]
Office space (area)		32,500		32,500
Second Expansion Premises
Lessee, Lease, Description [Line Items]
Office space (area)		65,222		65,222
Corporate Headquarters Lease
Lessee, Lease, Description [Line Items]
Office space (area)		113,000		113,000
Number of office space locations | item				2
Term of lease		84 months		84 months
Renewal term of lease		5 years		5 years
"First Space" Sublease
Lessee, Lease, Description [Line Items]
Number of office space locations				88,000
"Second Space" Sublease
Lessee, Lease, Description [Line Items]
Number of office space locations				25,000
Corporate Headquarters Lease Amendment
Lessee, Lease, Description [Line Items]
Annual lease payment | $				$ 9,300
Term of lease		48 months		48 months
Tukwila, WA Lease
Lessee, Lease, Description [Line Items]
Office space (area)		10,000		10,000
Term of lease		62 months		62 months
Renewal term of lease		5 years		5 years
San Carlos, CA Sublease
Lessee, Lease, Description [Line Items]
Office space (area)		25,879		25,879
Term of lease		48 months		48 months
Sublease receivable | $		$ 1,900		$ 1,900
San Carlos, CA Sublease Amendment | Rentable square feet surrendered in lease amendment
Lessee, Lease, Description [Line Items]
Office space (area)		25,879		25,879
South San Francisco, CA Lease
Lessee, Lease, Description [Line Items]
Office space (area)		11,395		11,395
Annual lease payment | $				$ 900
Term of lease		36 months		36 months
Laboratory space in Canada
Lessee, Lease, Description [Line Items]
Office space (area)	7,107
Annual lease payment | $	$ 200
Term of lease	24 months