Condensed Consolidated Balance Sheets - USD ($) $ in Thousands	Mar. 31, 2022	Dec. 31, 2021
Current assets:
Cash and cash equivalents	$ 158,298	$ 84,386
Restricted cash	228	228
Short-term investments	593,660	829,896
Accounts receivable, net of allowance of $2,392 in 2022 and $2,429 in 2021	167,862	122,074
Inventory	25,048	26,909
Prepaid expenses and other current assets, net	35,130	29,645
Total current assets	980,226	1,093,138
Property and equipment, net	78,361	65,516
Operating lease right-of-use assets	64,401	59,013
Other assets	21,676	18,820
Total assets	1,144,664	1,236,487
Current liabilities:
Accounts payable	18,070	27,206
Accrued compensation	32,396	40,941
Other accrued liabilities	116,637	93,353
Deferred revenue, current portion	13,914	7,404
Short-term debt financing	50,055	50,052
Total current liabilities	231,072	218,956
Long-term debt financing	280,706	280,394
Deferred revenue, long-term portion	20,543	21,318
Operating lease liabilities, long-term portion	67,477	61,036
Other long-term liabilities	2,531	1,479
Total liabilities	602,329	583,183
Commitments and contingencies (Note 8)
Stockholders' equity:
Common stock, $0.0001 par value: 750,000 shares authorized at both March 31, 2022 and December 31, 2021, respectively; 96,259 and 95,140 shares issued and outstanding at March 31, 2022 and December 31, 2021, respectively	10	10
Additional paid in capital	2,089,660	2,050,417
Accumulated deficit	(1,533,431)	(1,394,836)
Accumulated other comprehensive loss	(13,904)	(2,287)
Total stockholders' equity	542,335	653,304
Total liabilities and stockholders' equity	$ 1,144,664	$ 1,236,487