Consolidated Balance Sheets - USD ($) $ in Thousands	Dec. 31, 2021	Dec. 31, 2020
Current assets:
Cash and cash equivalents	$ 84,386	$ 48,668
Restricted cash	228	187
Short-term investments	829,896	688,606
Accounts receivable, net of allowance of $2,429 in 2021 and $3,080 in 2020	122,074	78,565
Inventory	26,909	20,031
Prepaid expenses and other current assets, net	29,645	26,606
Total current assets	1,093,138	862,663
Property and equipment, net	65,516	33,348
Operating lease right-of-use assets	59,013	21,399
Other assets	18,820	14,743
Total assets	1,236,487	932,153
Current liabilities:
Accounts payable	27,206	8,096
Accrued compensation	40,941	30,371
Other accrued liabilities	93,353	60,407
Deferred revenue, current portion	7,404	50,125
Short-term debt financing	50,052	50,054
Total current liabilities	218,956	199,053
Long-term debt financing	280,394	202,493
Deferred revenue, long-term portion	21,318	22,805
Operating lease liabilities, long-term portion	61,036	21,246
Other long-term liabilities	1,479	320
Total liabilities	583,183	445,917
Commitments and contingencies (Note 8)
Stockholders' equity:
Common stock, $0.0001 par value: 750,000 shares authorized at December 31, 2021 and 2020, respectively; 95,140 and 86,223 shares issued and outstanding at December 31, 2021 and 2020, respectively	10	9
Additional paid in capital	2,050,417	1,411,286
Accumulated deficit	(1,394,836)	(929,318)
Accumulated other comprehensive gain (loss)	(2,287)	4,259
Total stockholders' equity	653,304	486,236
Total liabilities and stockholders' equity	$ 1,236,487	$ 932,153