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Summary of Significant Accounting Policies - Liquidity Matters (Details) - USD ($)
$ / shares in Units, $ in Thousands
1 Months Ended 3 Months Ended 6 Months Ended
Jul. 31, 2021
May 31, 2021
Sep. 30, 2020
Apr. 30, 2020
Oct. 31, 2019
Apr. 30, 2019
Jun. 30, 2021
Jun. 30, 2020
Jun. 30, 2021
Jun. 30, 2020
Dec. 31, 2020
Dec. 31, 2019
Policies                        
Net (loss) income             $ (116,026) $ (59,637) $ (179,879) $ (95,009)    
Accumulated deficit             1,102,999   1,102,999   $ 929,318  
Cash, cash equivalents and restricted cash             63,039 77,377 63,039 77,377 48,855 $ 61,981
Marketable securities             517,432   517,432   688,606  
Short-term Credit Line, outstanding balance             $ 50,049   $ 50,049   $ 50,054  
Contractual commitment for development and option agreement   $ 10,000                    
Payment for third party assets if purchase option is exercised   $ 290,000                    
Common stock, shares issued             88,498,000   88,498,000   86,223,000  
Net proceeds                   278,317    
Loss on Debt Extinguishment               $ 5,848   $ 5,848    
Convertible Notes                        
Policies                        
Outstanding principal balance       $ 287,500     $ 287,500   $ 287,500      
Per annum interest rate (as a percent)       2.25%         2.25%      
Net proceeds       $ 278,300                
Equity offering                        
Policies                        
Common stock, shares issued     4,791,665   6,571,428 6,052,631            
Stock issued (in dollars per share)     $ 60.00   $ 35 $ 19            
Payment of offering expenses     $ 300   $ 400 $ 600            
Proceeds from issuance of common stock     $ 271,000   $ 216,200 $ 108,100            
Equity offering | Subsequent Event                        
Policies                        
Common stock, shares issued 5,175,000                      
Stock issued (in dollars per share) $ 113                      
Payment of offering expenses $ 400                      
Proceeds from issuance of common stock $ 551,200