Condensed Consolidated Statements of Operations and Comprehensive Loss - USD ($) shares in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2020	Sep. 30, 2019	Sep. 30, 2020	Sep. 30, 2019
Revenues
Total revenues	$ 98,143,000	$ 77,909,000	$ 278,627,000	$ 219,088,000
Cost and expenses
Research and development	26,421,000	12,796,000	67,651,000	36,355,000
Selling, general and administrative	75,678,000	56,715,000	209,547,000	147,589,000
Gain from disposal of business		(14,388,000)		(14,388,000)
Total cost and expenses	153,920,000	99,003,000	420,936,000	300,564,000
Loss from operations	(55,777,000)	(21,094,000)	(142,309,000)	(81,476,000)
Interest expense	(4,270,000)	(2,672,000)	(10,772,000)	(8,117,000)
Interest and other income, net	1,749,000	673,000	5,661,000	1,962,000
Loss on debt extinguishment			(5,848,000)
Loss before income taxes	(58,298,000)	(23,093,000)	(153,268,000)	(87,631,000)
Income tax expense	(25,000)	(44,000)	(63,000)	(2,013,000)
Net loss	(58,323,000)	(23,137,000)	(153,331,000)	(89,644,000)
Unrealized gain (loss) on available-for-sale securities, net of tax	(600,000)	63,000	4,251,000	1,410,000
Comprehensive loss	$ (58,923,000)	$ (23,074,000)	$ (149,080,000)	$ (88,234,000)
Net loss per share (Note 12):
Basic and diluted (in dollars per share)	$ (0.72)	$ (0.33)	$ (1.93)	$ (1.33)
Weighted-average number of shares used in computing basic and diluted net loss per share:
Basic and diluted (in shares)	80,908	70,456	79,430	67,198
Product
Revenues
Total revenues	$ 93,286,000	$ 66,936,000	$ 260,746,000	$ 195,399,000
Cost and expenses
Cost of revenues	46,873,000	40,138,000	131,124,000	123,125,000
Licensing and other
Revenues
Total revenues	4,857,000	10,973,000	17,881,000	23,689,000
Cost and expenses
Cost of revenues	$ 4,948,000	$ 3,742,000	$ 12,614,000	$ 7,883,000