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Condensed Consolidated Statements of Operations and Comprehensive Loss - USD ($)
shares in Thousands
3 Months Ended 6 Months Ended
Jun. 30, 2020
Jun. 30, 2019
Jun. 30, 2020
Jun. 30, 2019
Revenues        
Total revenues $ 86,472,000 $ 74,355,000 $ 180,484,000 $ 141,179,000
Cost and expenses        
Cost of revenues 42,731,000 41,382,000 84,251,000 82,987,000
Research and development 23,005,000 12,124,000 41,230,000 23,559,000
Selling, general and administrative 68,188,000 47,042,000 133,869,000 90,874,000
Total cost and expenses 138,132,000 102,991,000 267,016,000 201,561,000
Loss from operations (51,660,000) (28,636,000) (86,532,000) (60,382,000)
Interest expense (4,038,000) (2,721,000) (6,502,000) (5,445,000)
Interest and other income, net 1,924,000 836,000 3,911,000 1,289,000
Loss on debt extinguishment (5,848,000)   (5,848,000)  
Loss before income taxes (59,622,000) (30,521,000) (94,971,000) (64,538,000)
Income tax expense (15,000) (1,895,000) (38,000) (1,969,000)
Net loss (59,637,000) (32,416,000) (95,009,000) (66,507,000)
Unrealized gain on available-for-sale securities, net of tax 104,000 1,061,000 4,850,000 1,347,000
Comprehensive loss $ (59,533,000) $ (31,355,000) $ (90,159,000) $ (65,160,000)
Net loss per share (Note 12):        
Basic and diluted (in dollars per share) $ (0.75) $ (0.48) $ (1.21) $ (1.01)
Weighted-average number of shares used in computing basic and diluted net loss per share:        
Basic and diluted (in shares) 79,069 68,224 78,681 65,542
Product        
Revenues        
Total revenues $ 80,414,000 $ 65,099,000 $ 167,460,000 $ 128,463,000
Licensing and other        
Revenues        
Total revenues 6,058,000 9,256,000 13,024,000 12,716,000
Cost and expenses        
Cost of revenues $ 4,208,000 $ 2,443,000 $ 7,666,000 $ 4,141,000