Summary of Significant Accounting Policies (Tables)

12 Months Ended

Dec. 31, 2018

Accounting Standards Update 2014-09

Summary Of Significant Accounting Policies [Line Items]

Schedule of cumulative-effect adjustment

Upon the adoption of ASC 606, the Company revised the following selected amounts in its consolidated balance sheet from amounts previously reported:

	December 31, 2017
	As Previously		Adoption of
	Reported		ASC 606		As Revised
	(in thousands)
Accounts receivable, net of allowance	$	8,252	$	35,837	$	44,089
Other accrued liabilities		33,207		50		33,257
Accumulated deficit	$	(482,162)	$	35,787	$	(446,375)

Upon the adoption of ASC 606, the Company restated the following selected amounts in its consolidated statements of operations and comprehensive loss from amounts previously reported:

	Year ended December 31, 2017
	As Previously		Adoption of
	Reported		ASC 606		As Revised
	(in thousands)
Product revenues	$	205,489	$	(1,712)	$	203,777
Licensing and other revenues		5,450		398		5,848
Total revenues		210,939		(1,314)		209,625
Loss from operations		(134,027)		(1,314)		(135,341)
Net loss		(136,314)		(1,314)		(137,628)
Net loss per share:
Basic	$	(2.56)	$	(0.02)	$	(2.58)
Diluted	$	(2.56)	$	(0.03)	$	(2.59)

	Year ended December 31, 2016
	As Previously		Adoption of
	Reported		ASC 606		As Revised
	(in thousands)
Product revenues	$	213,968	$	(4,562)	$	209,406
Licensing and other revenues		3,106		—		3,106
Total revenues		217,074		(4,562)		212,512
Loss from operations		(96,488)		(4,562)		(101,050)
Net loss		(95,765)		(4,562)		(100,327)
Net loss per share:
Basic	$	(1.86)	$	(0.09)	$	(1.95)
Diluted	$	(1.86)	$	(0.09)	$	(1.95)

The Company restated the following selected amounts in its consolidated statements of cash flows from amounts previously reported as a result of the adoption of ASC 606, as well as the adoption of ASU 2016-18 regarding the new financial statement presentation requirements for restricted cash:

	Year ended December 31, 2017
	As Previously		Adoption of		Adoption of
	Reported		ASU 2016-18		ASC 606		As Revised
	(in thousands)
Operating activities:
Net loss	$	(136,314)	$	—	$	(1,314)	$	(137,628)
Changes in operating assets and liabilities:
Accounts receivable		5,001		—		1,314		6,315
Net cash used in operating activities		(96,792)		(1,033)		—		(97,825)
Cash, cash equivalents and restricted cash, beginning of period		15,256		1,434		—		16,690
Cash, cash equivalents and restricted cash, end of period	$	12,620	$	401	$	—	$	13,021

	Year ended December 31, 2016
	As Previously		Adoption of		Adoption of
	Reported		ASU 2016-18		ASC 606		As Revised
	(in thousands)
Operating activities:
Net loss	$	(95,765)	$	—	$	(4,562)	$	(100,327)
Changes in operating assets and liabilities:
Accounts receivable		(8,518)		—		4,562		(3,956)
Net cash used in operating activities		(73,902)		(150)		—		(74,052)
Cash, cash equivalents and restricted cash, beginning of period		28,947		1,584		—		30,531
Cash, cash equivalents and restricted cash, end of period	$	15,256	$	1,434	$	—	$	16,690

Accounting Standards Update 2016-18

Summary Of Significant Accounting Policies [Line Items]

Schedule of reconciliation of restricted cash

	December 31,		December 31,		December 31,		December 31,
	2018		2017		2016		2015
	(in thousands)
Cash and cash equivalents in balance sheet	$	46,407	$	12,620	$	15,256	$	28,947
Restricted cash, current portion in balance sheet		4,597		59		1,092		901
Restricted cash in other assets in balance sheet		—		342		342		683
Total cash, cash equivalents and restricted cash in statements of cash flows	$	51,004	$	13,021	$	16,690	$	30,531

Schedule of cumulative-effect adjustment

The Company restated the following selected amounts in its consolidated statements of cash flows from amounts previously reported as a result of the adoption of ASC 606, as well as the adoption of ASU 2016-18 regarding the new financial statement presentation requirements for restricted cash:

	Year ended December 31, 2017
	As Previously		Adoption of		Adoption of
	Reported		ASU 2016-18		ASC 606		As Revised
	(in thousands)
Operating activities:
Net loss	$	(136,314)	$	—	$	(1,314)	$	(137,628)
Changes in operating assets and liabilities:
Accounts receivable		5,001		—		1,314		6,315
Net cash used in operating activities		(96,792)		(1,033)		—		(97,825)
Cash, cash equivalents and restricted cash, beginning of period		15,256		1,434		—		16,690
Cash, cash equivalents and restricted cash, end of period	$	12,620	$	401	$	—	$	13,021

	Year ended December 31, 2016
	As Previously		Adoption of		Adoption of
	Reported		ASU 2016-18		ASC 606		As Revised
	(in thousands)
Operating activities:
Net loss	$	(95,765)	$	—	$	(4,562)	$	(100,327)
Changes in operating assets and liabilities:
Accounts receivable		(8,518)		—		4,562		(3,956)
Net cash used in operating activities		(73,902)		(150)		—		(74,052)
Cash, cash equivalents and restricted cash, beginning of period		28,947		1,584		—		30,531
Cash, cash equivalents and restricted cash, end of period	$	15,256	$	1,434	$	—	$	16,690