Summary of Significant Accounting Policies (Tables)

9 Months Ended

Sep. 30, 2018

Summary Of Significant Accounting Policies [Line Items]

Schedule of reconciliation of restricted cash

	September 30,		December 31,		September 30,		December 31,
	2018		2017		2017		2016
	(in thousands)
Cash and cash equivalents in balance sheet	$	34,535	$	12,620	$	11,211	$	15,256
Restricted cash, current portion in balance sheet		4,222		59		45		1,092
Restricted cash in other assets in balance sheet		342		342		342		342
Total cash, cash equivalents and restricted cash in statements of cash flows	$	39,099	$	13,021	$	11,598	$	16,690

Schedule of Accumulated Other Comprehensive Loss

	Balance at						Balance at
	December 31,				Reclassification		September 30,
	2017		Increase		Adjustment		2018
	(in thousands)
Unrealized (loss) gain on available-for-sale securities, net of tax	$	(766)	$	(171)	$	43	$	(894)
Total accumulated other comprehensive (loss) income, net of tax	$	(766)	$	(171)	$	43	$	(894)

Accounting Standards Update 2014-09

Summary Of Significant Accounting Policies [Line Items]

Schedule of cumulative-effect adjustment

Upon the adoption of ASC 606, the Company revised the following selected amounts in its condensed consolidated balance sheet from amounts previously reported:

	December 31, 2017
	As Previously		Adoption of
	Reported		ASC 606		As Revised
	(in thousands)
Accounts receivable, net of allowance	$	8,252	$	35,837	$	44,089
Other accrued liabilities		33,207		50		33,257
Accumulated deficit	$	(482,162)	$	35,787	$	(446,375)

Upon the adoption of ASC 606, the Company restated the following selected amounts in its unaudited condensed consolidated statements of operations and comprehensive loss from amounts previously reported:

	Three months ended September 30, 2017
	As Previously		Adoption of
	Reported		ASC 606		As Revised
	(in thousands)
Product revenues	$	55,331	$	(819)	$	54,512
Licensing and other revenues		1,325		73		1,398
Total revenues		56,656		(746)		55,910
Loss from operations		(25,043)		(746)		(25,789)
Net loss		(27,119)		(746)		(27,865)
Net loss per share:
Basic		(0.51)		(0.01)		(0.52)
Diluted	$	(0.51)	$	(0.01)	$	(0.52)

	Nine months ended September 30, 2017
	As Previously		Adoption of
	Reported		ASC 606		As Revised
	(in thousands)
Product revenues	$	153,520	$	315	$	153,835
Licensing and other revenues		3,654		86		3,740
Total revenues		157,174		401		157,575
Loss from operations		(89,111)		401		(88,710)
Net loss		(90,812)		401		(90,411)
Net loss per share:
Basic		(1.71)		0.01		(1.70)
Diluted	$	(1.71)	$	0.01	$	(1.70)

	Nine months ended September 30, 2017
	As Previously		Adoption of		Adoption of
	Reported		ASU 2016-18		ASC 606		As Revised
	(in thousands)
Operating activities:
Net loss	$	(90,812)	$	—	$	401	$	(90,411)
Changes in operating assets and liabilities:
Accounts receivable		6,147		—		(401)		5,746
Net cash used in operating activities		(68,649)		(1,047)		—		(69,696)
Cash, cash equivalents and restricted cash, beginning of period		15,256		1,434		—		16,690
Cash, cash equivalents and restricted cash, end of period	$	11,211	$	387	$	—	$	11,598

Accounting Standards Update 2016-18

Summary Of Significant Accounting Policies [Line Items]

Schedule of cumulative-effect adjustment

	Nine months ended September 30, 2017
	As Previously		Adoption of		Adoption of
	Reported		ASU 2016-18		ASC 606		As Revised
	(in thousands)
Operating activities:
Net loss	$	(90,812)	$	—	$	401	$	(90,411)
Changes in operating assets and liabilities:
Accounts receivable		6,147		—		(401)		5,746
Net cash used in operating activities		(68,649)		(1,047)		—		(69,696)
Cash, cash equivalents and restricted cash, beginning of period		15,256		1,434		—		16,690
Cash, cash equivalents and restricted cash, end of period	$	11,211	$	387	$	—	$	11,598