Condensed Consolidated Statements of Operations and Comprehensive Loss - USD ($) shares in Thousands, $ in Thousands	3 Months Ended
	Mar. 31, 2017	Mar. 31, 2016
Revenues
Product revenues	$ 45,913	$ 61,136
Licensing and other revenues	988	766
Total revenues	46,901	61,902
Cost and expenses
Cost of product revenues	33,088	32,340
Cost of licensing and other revenues	612
Research and development	12,650	8,759
Selling, general and administrative	37,582	30,408
Total cost and expenses	83,932	71,507
Loss from operations	(37,031)	(9,605)
Interest expense	(183)	(115)
Interest and other income	1,300	1,035
Loss before income taxes	(35,914)	(8,685)
Income tax expense	(47)
Net loss	(35,961)	(8,685)
Unrealized gain on available-for-sale securities, net of tax	200	1,811
Comprehensive loss	$ (35,761)	$ (6,874)
Net loss per share (Note 11):
Basic (in dollars per share)	$ (0.68)	$ (0.17)
Diluted (in dollars per share)	$ (0.70)	$ (0.17)
Weighted-average number of shares used in computing basic and diluted net loss per share:
Basic (in shares)	52,758	50,439
Diluted (in shares)	53,043	50,439