Net Loss per Share (Tables)

3 Months Ended

Mar. 31, 2017

Net Loss per Share

Basic and diluted net loss per common share

	Three months ended
	March 31,
(in thousands, except per share data)	2017		2016
Numerator:
Net loss used to compute net loss per share, basic	$	(35,961)	$	(8,685)
Less:  Remeasurement gain on warrant liability		(1,042)		—
Net loss used to compute net loss per share, diluted	$	(37,003)		(8,685)
Denominator:
Weighted-average shares outstanding		52,758		50,803
Less:  weighted-average unvested shares subject to repurchase		—		(364)
Weighted-average number of shares used in computing net loss per share, basic		52,758		50,439
Add:  incremental shares from assumed exercise of warrants		285		—
Weighted-average number of shares used in computing net loss per share, diluted		53,043		50,439
Net loss per share, basic	$	(0.68)	$	(0.17)
Net loss per share, diluted	$	(0.70)	$	(0.17)

Potentially dilutive shares not included in the calculation of dilutive EPS

	March 31,
	2017	2016
	(in thousands)
Options to purchase common stock	8,774	8,395
Warrants to purchase common stock	—	377
Restricted stock units	138	—
Employee stock purchase plan	207	—
	9,119	8,772