Net Loss per Share (Tables)

12 Months Ended

Dec. 31, 2016

Net Loss per Share

Basic and diluted net loss per common share

	Year ended December 31,
(in thousands, except per share data)	2016		2015		2014
Basic and diluted loss per share:
Net loss	$	(95,765)	$	(70,275)	$	(5,152)
Weighted-average common shares outstanding		51,667		27,687		6,670
Less:  weighted-average unvested common shares subject to repurchase		(91)		(1,483)		(1,870)
Weighted-average number of shares used in computing net loss per share, basic and diluted		51,576		26,204		4,800
Basic and diluted net loss per share	$	(1.86)	$	(2.68)	$	(1.07)

Potentially dilutive shares not included in the calculation of dilutive EPS

	Year ended December 31,
	2016	2015	2014
Options to purchase common stock	9,043	9,316	8,450
Warrants to purchase common stock	377	377	864
Restricted stock units	159	—	—
Employee stock purchase plan	90	—	—
Common stock subject to repurchase	—	1,307	1,690
Convertible preferred stock	—	—	31,397
	9,669	11,000	42,401