Condensed Consolidated Statements of Operations and Comprehensive Loss - USD ($) shares in Thousands, $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2016	Jun. 30, 2015	Jun. 30, 2016	Jun. 30, 2015
Revenues
Product revenues	$ 51,231	$ 44,519	$ 112,367	$ 91,418
Other revenues	753	568	1,519	1,104
Total revenues	51,984	45,087	113,886	92,522
Cost and expenses
Cost of product revenues	30,973	25,732	63,313	50,575
Research and development	10,299	6,741	19,058	12,371
Selling, general and administrative	33,227	28,086	63,635	51,325
Total cost and expenses	74,499	60,559	146,006	114,271
Loss from operations	(22,515)	(15,472)	(32,120)	(21,749)
Interest Expense	(122)	(1,203)	(237)	(2,213)
Interest expense from changes in the fair value of long-term debt		(322)		(2,122)
Interest and other (expense) income, net	(519)	(2,684)	516	(3,601)
Net loss	(23,156)	(19,681)	(31,841)	(29,685)
Unrealized gain on available-for-sale securities, net of tax	548		2,359
Comprehensive loss	$ (22,608)	$ (19,681)	$ (29,482)	$ (29,685)
Basic and diluted net loss per share (in dollars per share)	$ (0.46)	$ (3.58)	$ (0.63)	$ (5.50)
Weighted-average number of shares used in computing basic and diluted net loss per share	51,445	5,494	50,942	5,393