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Net Loss per Share (AntiDil) (Details) - shares
12 Months Ended
Dec. 31, 2015
Dec. 31, 2014
Dec. 31, 2013
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]      
Potentially dilutive shares not included in the calculation of diluted EPS 11,000 42,401 33,941
Employee and non-employee stock options      
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]      
Potentially dilutive shares not included in the calculation of diluted EPS 9,316 8,450 4,406
Warrants to purchase common stock      
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]      
Potentially dilutive shares not included in the calculation of diluted EPS 377 864 410
Common stock subject to repurchase      
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]      
Potentially dilutive shares not included in the calculation of diluted EPS 1,307 1,690 2,077
Redeemable convertible preferred stock      
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]      
Potentially dilutive shares not included in the calculation of diluted EPS   31,397 27,048