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Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Dec. 31, 2023
Operating activities:      
Net loss $ (208,160) $ (190,426) $ (434,801)
Adjustments to reconcile net loss to net cash provided by (used in) operating activities:      
Depreciation and amortization 41,764 30,968 24,097
Amortization of acquired intangible assets 1,720    
Expensed in-process research and development     2,679
Non-cash lease expense 20,198 15,325 14,519
Stock-based compensation 354,404 274,428 191,808
Amortization of premiums and accretion of purchase discounts on investment securities 32 (618) 1,087
Change in fair value of warrants and preferred stock of related party equity investment (3,235)    
Foreign exchange adjustment 17 462 265
Amortization of debt discount and issuance cost   991 1,292
Non-cash interest expense (39) 2,835 52
Non-cash expense recovery (1,445) (442)  
Changes in operating assets and liabilities:      
Accounts receivable 20,752 (35,876) (33,904)
Inventory (20,871) (3,985) (5,353)
Operating lease right-of-use assets 4,229   8,354
Prepaid expenses and other assets (8,634) 10,807 (26,072)
Accounts payable 753 13,210 (15,458)
Accrued compensation 60,269 40,328 21,619
Deferred tax liability (60,800)    
Operating lease liabilities (19,751) (16,819) (12,448)
Other accrued liabilities 31,345 (6,376) 10,347
Deferred revenue 2,753 852 4,962
Net cash provided by (used in) operating activities 215,301 135,664 (246,955)
Investing activities:      
Purchases of investments   (122,010) (98,303)
Proceeds from sale of investments   24,822  
Proceeds from maturity of investments 23,000 314,400 306,000
Purchases of property and equipment, net (106,188) (66,423) (39,199)
Purchase of intangible assets, net (33,000) (10,495)  
Investment in related party   (2,670)  
Cash paid for business combination, net (16,021)    
Net cash (used in) provided by investing activities (132,209) 137,624 168,498
Financing activities:      
Proceeds from exercise of stock options 22,536 12,988 3,892
Proceeds from issuance of common stock under employee stock purchase plan 25,037 17,298 15,128
Proceeds from public offering, net of issuance cost     235,441
Stock issuance costs (112)    
Cash redemption on Convertible Note   (82)  
Net cash provided by financing activities 47,461 30,204 254,461
Net change in cash, cash equivalents and restricted cash 130,553 303,492 176,004
Beginning cash, cash equivalents and restricted cash 945,587 642,095 466,091
Ending cash, cash equivalents and restricted cash 1,076,140 945,587 642,095
Supplemental disclosure of cash flow information:      
Cash paid for income taxes, net 499 1,307 295
Cash paid for interest 4,069 7,897 11,346
Non-cash activities:      
Purchases of property and equipment in accounts payable and accruals (1,014) 9,374 1,582
Acquisition of warrants   9,424  
Amounts accrued for acquisition of intangible assets 3,000 1,400  
Contingent consideration for business combination 118,360    
Issuance of common stock for business combination 287,428    
Issuance of common stock for IPR&D milestone     14,435
Issuance of common stock for bonuses 32,875 24,071 19,774
Stock-based compensation included in capitalized software development costs $ 2,899 2,263 $ 629
Debt and interest converted into equity   $ 286,730