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Condensed Consolidated Statements of Operations and Comprehensive Loss - USD ($)
shares in Thousands, $ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2025
Sep. 30, 2024
Sep. 30, 2025
Sep. 30, 2024
Revenues        
Total revenues $ 592,183 $ 439,758 $ 1,640,615 $ 1,220,850
Cost and expenses        
Research and development 173,412 96,931 448,917 274,677
Selling, general and administrative 308,546 214,154 885,962 606,397
Total cost and expenses 689,759 479,096 1,927,741 1,378,404
Loss from operations (97,576) (39,338) (287,126) (157,554)
Interest expense (1,045) (3,142) (3,078) (9,393)
Interest and other income, net 11,284 11,618 35,441 32,342
Loss before income taxes (87,337) (30,862) (254,763) (134,605)
Income tax expense (207) (730) (655) (2,050)
Net loss (87,544) (31,592) (255,418) (136,655)
Unrealized (loss) gain on available-for-sale securities, net of tax 100 593 157 2,320
Comprehensive loss $ (87,444) $ (30,999) $ (255,261) $ (134,335)
Net loss per share (Note 12):        
Basic (in dollars per share) $ (0.64) $ (0.26) $ (1.88) $ (1.12)
Diluted (in dollars per share) $ (0.64) $ (0.26) $ (1.88) $ (1.12)
Weighted-average number of shares used in computing basic and diluted net loss per share:        
Basic (in shares) 137,187 123,775 136,181 122,486
Diluted (in shares) 137,187 123,775 136,181 122,486
Product        
Revenues        
Total revenues $ 590,197 $ 436,127 $ 1,634,660 $ 1,212,163
Cost and expenses        
Cost of revenues 207,253 167,657 591,397 496,340
Licensing and other        
Revenues        
Total revenues 1,986 3,631 5,955 8,687
Cost and expenses        
Cost of revenues $ 548 $ 354 $ 1,465 $ 990