X0306 4 2015-02-25 0 0001328143 Adamas Pharmaceuticals Inc ADMS 0001604541 Went Gregory T C/O ADAMAS PHARMACEUTICALS, INC. 1900 POWELL ST., SUITE 750 EMERYVILLE CA 94608 1 1 1 0 Chief Executive Officer Stock Option (Right to Buy) 17.31 2015-02-25 4 A 0 75000 0.00 A 2025-02-24 Common Stock 75000 75000 D The Option shares shall vest as follows: 1/48th of the option shares shall vest on the 1st of each month beginning with March 1, 2015, subject to Reporting Person's Continuous Service (as defined in the Issuer's 2014 Equity Incentive Plan) as of each such date. /s/Grace Shin, as Attorney-in-Fact 2015-02-27