Consolidated Statements of Stockholders' Equity - USD ($) $ in Thousands	Total	Public Offering [Member]	Common Stock [Member]	Common Stock [Member] Public Offering [Member]	Common Stock [Member] At-the-market Offering [Member]	Additional Paid-in Capital [Member]	Additional Paid-in Capital [Member] Public Offering [Member]	Additional Paid-in Capital [Member] At-the-market Offering [Member]	Accumulated Deficit [Member]
Beginning balance at Dec. 31, 2020	$ 127,199		$ 25			$ 253,943			$ (126,769)
Beginning balance (Shares) at Dec. 31, 2020			24,786,324
Issuance of common stock		$ 55,602		$ 3			$ 55,599
Issuance of common stock (Shares)				3,000,000
Issuance of common stock upon exercise of stock options	1,307					1,307
Issuance of common stock upon exercise of stock options (Shares)			333,417
Issuance of common stock under employee stock purchase plan	104					104
Issuance of common stock under employee stock purchase plan (Shares)			13,627
Stock-based compensation expense	8,505					8,505
Net loss	(68,741)								(68,741)
Ending balance at Dec. 31, 2021	123,976		$ 28			319,458			(195,510)
Ending balance (Shares) at Dec. 31, 2021			28,133,368
Issuance of common stock	4,067				$ 1			$ 4,066
Issuance of common stock (Shares)					1,261,226
Issuance of common stock upon exercise of stock options	$ 29					29
Issuance of common stock upon exercise of stock options (Shares)	14,757		14,757
Issuance of common stock under employee stock purchase plan	$ 137					137
Issuance of common stock under employee stock purchase plan (Shares)			81,774
Stock-based compensation expense	8,403					8,403
Net loss	(79,464)								(79,464)
Ending balance at Dec. 31, 2022	$ 57,148		$ 29			$ 332,093			$ (274,974)
Ending balance (Shares) at Dec. 31, 2022			29,491,125