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License and Collaboration Agreements - Summary of Changes in the Total Contract Liability (Detail) - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2022
Mar. 31, 2021
Research and Development [Abstract]    
Balance at beginning of period $ 21,203 $ 45,201
Recognition of deferred revenue (2,869) (5,454)
Balance at end of period $ 18,334 $ 39,747