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Leases - Additional Information (Detail)
$ in Millions
1 Months Ended 12 Months Ended
Feb. 15, 2018
USD ($)
ft²
Mar. 31, 2021
USD ($)
ft²
Dec. 31, 2021
USD ($)
South San Francisco California      
Lessee Lease Description [Line Items]      
Lease expiration date     May 31, 2025
South San Francisco California | Line of Credit      
Lessee Lease Description [Line Items]      
Letter of credit maintained     $ 0.1
Letter of credit renewal term     12 months
Letter of credit, decrease from prior lease agreement     $ 0.1
Restricted cash related to letter of credit     $ 0.2
Thousand Oaks California      
Lessee Lease Description [Line Items]      
Lease agreement area of square feet of office, lab and warehouse space | ft²   33,659  
Lease initial term 15 years 10 years 6 months  
Contractual obligations $ 16.4 $ 21.0  
Percentage of annual increase in base rent   3.00%  
Operating lease, option to extend   0  
Lease option to extend additional term   5 years  
Lease agreement area of office, lab and cellular therapy manufacturing space | ft² 90,580    
Lease commencement date Feb. 15, 2018    
Lease extension term, option one 10 years    
Lease extension term, option two 9 years    
Thousand Oaks California | Additional Office Space      
Lessee Lease Description [Line Items]      
Lease expiration date     Feb. 28, 2026
Operating lease, option to extend     we have the option to extend the lease for an additional period of five years after the initial term.
Lease option to extend additional term     5 years
Operating lease, existence of option to extend [true false]     true
Thousand Oaks California | Line of Credit      
Lessee Lease Description [Line Items]      
Letter of credit issued, classified as long-term restricted cash $ 1.2    
Aurora Colorado      
Lessee Lease Description [Line Items]      
Lease expiration date     Apr. 30, 2024
Incremental contractual obligations under lease amendment     $ 0.2