Condensed Consolidated Statements of Changes in Stockholders' Equity (Unaudited) - USD ($) shares in Thousands, $ in Thousands	Total	Common Stock	Additional Paid-in Capital	Accumulated Other Comprehensive Income (Loss)	Accumulated Deficit
Beginning balance at Dec. 31, 2023	$ (99,231)	$ 0	$ 1,870,123	$ (204)	$ (1,969,150)
Beginning balance (in shares) at Dec. 31, 2023		4,258
Issuance of pre-funded warrants to purchase common stock through a registered direct offering, net of offering costs , value	14,823		14,823
Issuance of common stock through ATM facilities, net of commissions and offering costs, value	9,312		9,312
Issuance of common stock through ATM facilities, net of commissions and offering costs, shares		493
RSU settlements, net of shares withheld	(6)		(6)
RSU settlements, net of shares withheld, shares		63
Stock-based compensation expense	8,397		8,397
Net (loss) income	(31,752)				(31,752)
Unrealized gain (loss) on available-for-sale securities	149			149	0
Ending balance at Mar. 31, 2024	(98,308)	$ 0	1,902,649	(55)	(2,000,902)
Ending balance (in shares) at Mar. 31, 2024		4,814
Beginning balance at Dec. 31, 2023	(99,231)	$ 0	1,870,123	(204)	(1,969,150)
Beginning balance (in shares) at Dec. 31, 2023		4,258
Net (loss) income	(50,801)
Unrealized gain (loss) on available-for-sale securities	190
Ending balance at Jun. 30, 2024	(110,868)	$ 0	1,909,097	(14)	(2,019,951)
Ending balance (in shares) at Jun. 30, 2024		4,904
Beginning balance at Mar. 31, 2024	(98,308)	$ 0	1,902,649	(55)	(2,000,902)
Beginning balance (in shares) at Mar. 31, 2024		4,814
RSU settlements, net of shares withheld	(1)		(1)
RSU settlements, net of shares withheld, shares		81
Issuance of common stock pursuant to employee stock awards, shares		9
Issuance of common stock pursuant to employee stock awards	113		113
Stock-based compensation expense	6,336		6,336
Net (loss) income	(19,049)				(19,049)
Unrealized gain (loss) on available-for-sale securities	41			41	0
Ending balance at Jun. 30, 2024	(110,868)	$ 0	1,909,097	(14)	(2,019,951)
Ending balance (in shares) at Jun. 30, 2024		4,904
Beginning balance at Dec. 31, 2024	(97,283)	$ 1	1,957,261	8	(2,054,553)
Beginning balance (in shares) at Dec. 31, 2024		5,859
RSU settlements, net of shares withheld, shares		65
Stock-based compensation expense	4,209		4,209
Net (loss) income	38,010				38,010
Unrealized gain (loss) on available-for-sale securities	(8)			(8)
Ending balance at Mar. 31, 2025	(55,072)	$ 1	1,961,470	0	(2,016,543)
Ending balance (in shares) at Mar. 31, 2025		5,924
Beginning balance at Dec. 31, 2024	(97,283)	$ 1	1,957,261	8	(2,054,553)
Beginning balance (in shares) at Dec. 31, 2024		5,859
Net (loss) income	40,397
Unrealized gain (loss) on available-for-sale securities	(8)
Ending balance at Jun. 30, 2025	(35,041)	$ 1	1,979,114	0	(2,014,156)
Ending balance (in shares) at Jun. 30, 2025		6,978
Beginning balance at Mar. 31, 2025	$ (55,072)	$ 1	1,961,470	0	(2,016,543)
Beginning balance (in shares) at Mar. 31, 2025		5,924
Issuance of pre-funded warrants to purchase common stock through an underwritten registered direct offering, net of offering costs (in shares)	834
Issuance of pre-funded warrants to purchase common stock through a registered direct offering, net of offering costs , value	$ 14,843		14,843
RSU settlements, net of shares withheld	(1)		(1)
RSU settlements, net of shares withheld, shares		220
Issuance of common stock pursuant to employee stock awards	1		1
Stock-based compensation expense	2,801		2,801
Net (loss) income	2,387				2,387
Unrealized gain (loss) on available-for-sale securities	0
Ending balance at Jun. 30, 2025	$ (35,041)	$ 1	$ 1,979,114	$ 0	$ (2,014,156)
Ending balance (in shares) at Jun. 30, 2025		6,978