Description of Business (Detail) - USD ($) $ in Millions	1 Months Ended					6 Months Ended	12 Months Ended
	May 31, 2025	Mar. 31, 2025	Jan. 31, 2025	Jan. 31, 2024	Nov. 30, 2023	Jun. 30, 2025	Dec. 31, 2022	Nov. 01, 2023
License Collaboration And Manufacturing Agreements [Line Items]
Entity incorporation state						DE
Entity incorporation date						Aug. 01, 2012
Reduction in current workforce	30.00%	50.00%	50.00%	25.00%	30.00%			30.00%
Severance Costs	$ 1.4	$ 2.7	$ 7.1	$ 5.1	$ 6.7
HCRx Agreement [Member]
License Collaboration And Manufacturing Agreements [Line Items]
Proceeds from sale of future royalties, gross						$ 31.0	$ 31.0
Minimum cash repayment						185.00%
Maximum cash repayment						250.00%