Restructuring - Summary of future termination benefit payments (Details) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2025	Mar. 31, 2024
Restructuring Cost and Reserve [Line Items]
Total restructuring charges	$ 9,813	$ 4,751
Restructuring Charges, Statement of Income or Comprehensive Income [Extensible Enumeration]	Costs and Expenses	Costs and Expenses
General and administrative
Restructuring Cost and Reserve [Line Items]
Total restructuring charges	$ 1,464	$ 1,357
Research and development
Restructuring Cost and Reserve [Line Items]
Total restructuring charges	$ 8,349	$ 3,394