Condensed Consolidated Statements of Changes in Stockholders' Equity (Unaudited) - USD ($) shares in Thousands, $ in Thousands	Total	Common Stock	Additional Paid-in Capital	Accumulated Other Comprehensive Income (Loss)	Accumulated Deficit
Beginning balance at Dec. 31, 2023	$ (99,231)	$ 0	$ 1,870,123	$ (204)	$ (1,969,150)
Beginning balance (in shares) at Dec. 31, 2023		4,258
Issuance of pre-funded warrants to purchase common stock through a registered direct offering, net of offering costs of $177	14,823		14,823
Issuance of common stock through ATM facilities, net of commissions and offering costs, value	9,312		9,312
Issuance of common stock through ATM facilities, net of commissions and offering costs, shares		493
RSU settlements, net of shares withheld	(6)		(6)
RSU settlements, net of shares withheld, shares		63
Stock-based compensation expense	8,397		8,397
Net (loss) income	(31,752)				(31,752)
Unrealized gain (loss) on available-for-sale securities	149			149	0
Ending balance at Mar. 31, 2024	(98,308)	$ 0	1,902,649	(55)	(2,000,902)
Ending balance (in shares) at Mar. 31, 2024		4,814
Beginning balance at Dec. 31, 2024	(97,283)	$ 1	1,957,261	8	(2,054,553)
Beginning balance (in shares) at Dec. 31, 2024		5,859
RSU settlements, net of shares withheld, shares		65
Stock-based compensation expense	4,209		4,209
Net (loss) income	38,010				38,010
Unrealized gain (loss) on available-for-sale securities	(8)			(8)
Ending balance at Mar. 31, 2025	$ (55,072)	$ 1	$ 1,961,470	$ 0	$ (2,016,543)
Ending balance (in shares) at Mar. 31, 2025		5,924