Description of Business (Detail) - USD ($) $ in Millions	1 Months Ended				3 Months Ended	12 Months Ended
	Mar. 31, 2025	Jan. 31, 2025	Jan. 31, 2024	Nov. 30, 2023	Mar. 31, 2025	Dec. 31, 2022	Nov. 01, 2023
License Collaboration And Manufacturing Agreements [Line Items]
Entity incorporation state					DE
Entity incorporation date					Aug. 01, 2012
Reduction in current workforce	50.00%	50.00%	25.00%	30.00%	50.00%		30.00%
Severance Costs	$ 2.7	$ 7.1	$ 5.1	$ 6.7
Supplemental Unemployment Benefits, Severance Benefits	$ 2.7	$ 7.1	$ 5.1	$ 6.7	$ 2.7
HCRx Agreement [Member]
License Collaboration And Manufacturing Agreements [Line Items]
Proceeds from sale of future royalties, gross					$ 31.0	$ 31.0
Minimum cash repayment					185.00%
Maximum cash repayment					250.00%