Out-license Agreements - Additional Information (Detail) - USD ($) $ in Thousands	1 Months Ended					9 Months Ended	12 Months Ended
	Aug. 31, 2024	Jul. 31, 2024	Dec. 31, 2023	Dec. 31, 2022	Oct. 31, 2021	Sep. 30, 2022	Dec. 31, 2024	Dec. 31, 2023	Dec. 31, 2022	Mar. 31, 2024
License, Collaboration and Manufacturing Agreements [Line Items]
License and collaboration revenue							$ 0	$ 687
Deferred revenue - long-term, December 31, 2024			$ 37,562				0	37,562
Deferred revenue, revenue recognized							45,700
Revenue recognition, performance satisfied or partially satisfied prior period							900
Hcrx Agreement [Member]
License, Collaboration and Manufacturing Agreements [Line Items]
Proceeds from sale of future royalties, gross							$ 31,000		$ 31,000
Minimum Cash Repayment							185.00%
Maximum Cash Repayment							250.00%
Pierre Fabre Commercialization Agreement
License, Collaboration and Manufacturing Agreements [Line Items]
Upfront cash payment received			$ 20,000		$ 45,000
Payments received from sale of inventory	$ 15,500
Royalty eligible to receive term after first commercial sale			12 years		12 years
Development or sales-based milestone payments earned or received				$ 40,000		$ 30,000
Determined upfront payment constituted entire consideration included in transaction price					$ 45,000
Milestone payments				$ 40,000					$ 40,000	$ 20,000
Additional milestone payments		$ 20,000
Pierre Fabre Commercialization Agreement | Maximum
License, Collaboration and Manufacturing Agreements [Line Items]
Aggregate milestone payments entitle to receive upon achieving certain regulatory and commercial milestones					$ 308,000		$ 580,000
A&R Commercialization Agreement [Member]
License, Collaboration and Manufacturing Agreements [Line Items]
Additional Upfront Payment Included inTransaction Price							20,000
Regulatory Milestone		$ 20,000								$ 20,000
Costs Incurred Relatedto Performance Obligations Includedin R&D							$ 43,300	$ 0