Description of Business - Additional Information (Detail) - USD ($) $ in Millions	12 Months Ended
	Dec. 31, 2024	Dec. 31, 2022	Jan. 31, 2024	Jan. 08, 2024	Nov. 01, 2023	Aug. 08, 2022
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Entity incorporation state	DE
Entity incorporation date	Aug. 01, 2012
Reduction in current workforce percentage			25.00%	25.00%	30.00%	20.00%
Supplemental unemployment benefits, severance benefits			$ 5.1	$ 5.1	$ 6.7	$ 6.0
Hcrx Agreement [Member]
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Proceeds from sale of future revenues, net	$ 31.0	$ 31.0
Minimum Cash Repayment	185.00%
Maximum Cash Repayment	250.00%