Condensed Consolidated Statements of Changes in Stockholders' Equity (Unaudited) - USD ($) shares in Thousands, $ in Thousands	Total	Common Stock	Additional Paid-in Capital	Accumulated Other Comprehensive Income (Loss)	Accumulated Deficit
Beginning balance at Dec. 31, 2022	$ 126,640		$ 1,821,731	$ (2,067)	$ (1,693,024)
Beginning balance (in shares) at Dec. 31, 2022		3,837
Issuance of common stock through ATM facilities, net of commissions and offering costs, value	590		590
Issuance of common stock through ATM facilities, net of commissions and offering costs, shares		6
RSU settlements, net of shares withheld	(93)		(93)
RSU settlements, net of shares withheld, shares		19
Stock-based compensation expense	11,764		11,764
Net (loss) income	(74,771)				(74,771)
Unrealized gain (loss) on available-for-sale securities	830			830
Ending balance at Mar. 31, 2023	64,960		1,833,992	(1,237)	(1,767,795)
Ending balance (in shares) at Mar. 31, 2023		3,862
Beginning balance at Dec. 31, 2022	126,640		1,821,731	(2,067)	(1,693,024)
Beginning balance (in shares) at Dec. 31, 2022		3,837
Net (loss) income	(145,879)
Unrealized gain (loss) on available-for-sale securities	1,134
Ending balance at Jun. 30, 2023	7,454		1,847,290	(933)	(1,838,903)
Ending balance (in shares) at Jun. 30, 2023		4,044
Beginning balance at Mar. 31, 2023	64,960		1,833,992	(1,237)	(1,767,795)
Beginning balance (in shares) at Mar. 31, 2023		3,862
RSU settlements, net of shares withheld	(1)		(1)
Exercise of pre-funded warrants, Share		116
RSU settlements, net of shares withheld, shares		43
Issuance of common stock pursuant to employee stock awards, shares		23
Issuance of common stock pursuant to employee stock awards	747		747
Stock-based compensation expense	12,552		12,552
Net (loss) income	(71,108)				(71,108)
Unrealized gain (loss) on available-for-sale securities	304			304
Ending balance at Jun. 30, 2023	7,454		1,847,290	(933)	(1,838,903)
Ending balance (in shares) at Jun. 30, 2023		4,044
Beginning balance at Dec. 31, 2023	(99,231)		1,870,123	(204)	(1,969,150)
Beginning balance (in shares) at Dec. 31, 2023		4,258
Issuance of pre-funded warrants to purchase common stock through a registered direct offering, net of offering costs of $177	14,823		14,823
Issuance of common stock through ATM facilities, net of commissions and offering costs, value	9,312		9,312
Issuance of common stock through ATM facilities, net of commissions and offering costs, shares		493
RSU settlements, net of shares withheld	(6)		(6)
RSU settlements, net of shares withheld, shares		63
Stock-based compensation expense	8,397		8,397
Net (loss) income	(31,752)				(31,752)
Unrealized gain (loss) on available-for-sale securities	149			149
Ending balance at Mar. 31, 2024	(98,308)		1,902,649	(55)	(2,000,902)
Ending balance (in shares) at Mar. 31, 2024		4,814
Beginning balance at Dec. 31, 2023	(99,231)		1,870,123	(204)	(1,969,150)
Beginning balance (in shares) at Dec. 31, 2023		4,258
Net (loss) income	(50,801)
Unrealized gain (loss) on available-for-sale securities	190
Ending balance at Jun. 30, 2024	(110,868)		1,909,097	(14)	(2,019,951)
Ending balance (in shares) at Jun. 30, 2024		4,904
Beginning balance at Mar. 31, 2024	(98,308)		1,902,649	(55)	(2,000,902)
Beginning balance (in shares) at Mar. 31, 2024		4,814
RSU settlements, net of shares withheld	(1)		(1)
RSU settlements, net of shares withheld, shares		81
Issuance of common stock pursuant to employee stock awards, shares		9
Issuance of common stock pursuant to employee stock awards	113		113
Stock-based compensation expense	6,336		6,336
Net (loss) income	(19,049)				(19,049)
Unrealized gain (loss) on available-for-sale securities	41			41	0
Ending balance at Jun. 30, 2024	$ (110,868)		$ 1,909,097	$ (14)	$ (2,019,951)
Ending balance (in shares) at Jun. 30, 2024		4,904