Consolidated Statements of Stockholders' Equity (Deficit) - USD ($) shares in Thousands, $ in Thousands	Total	Common Stock	Additional Paid-in Capital	Accumulated Other Comprehensive (Loss) Income	Accumulated Deficit
Beginning balance at Dec. 31, 2021	$ 279,614	$ 9	$ 1,744,695	$ (368)	$ (1,464,722)
Beginning balance (in shares) at Dec. 31, 2021		91,671
Issuance of common stock through ATM facilities, net of commissions and offering costs, value	21,891		21,891
Issuance of common stock through ATM facilities, net of commissions and offering costs, shares		1,619
RSU settlements, net of shares withheld	(623)	$ 1	(624)
RSU settlements, net of shares withheld, shares		2,204
Issuance of common stock pursuant to employee stock awards	1,921		1,921
Issuance of common stock pursuant to employee stock awards, shares		433
Stock-based compensation expense	53,838		53,838
Net Income (Loss)	(228,302)				(228,302)
Unrealized gain (loss) on available-for-sale securities	(1,699)			(1,699)
Ending balance at Dec. 31, 2022	126,640	$ 10	1,821,721	(2,067)	(1,693,024)
Ending balance (in shares) at Dec. 31, 2022		95,927
Issuance of common stock through ATM facilities, net of commissions and offering costs, value	2,172	$ 1	2,171
Issuance of common stock through ATM facilities, net of commissions and offering costs, shares		3,038
Exercise of pre-funded warrants, shares		2,916
RSU settlements, net of shares withheld	(94)		(94)
RSU settlements, net of shares withheld, shares		3,670
Issuance of common stock pursuant to employee stock awards	928		928
Issuance of common stock pursuant to employee stock awards, shares		896
Stock-based compensation expense	45,386		45,386
Net Income (Loss)	(276,126)				(276,126)
Unrealized gain (loss) on available-for-sale securities	1,863			1,863
Ending balance at Dec. 31, 2023	$ (99,231)	$ 11	$ 1,870,112	$ (204)	$ (1,969,150)
Ending balance (in shares) at Dec. 31, 2023		106,447