Out-license Agreements - Additional Information (Detail) - USD ($) $ in Thousands	1 Months Ended			9 Months Ended	12 Months Ended
	Dec. 31, 2023	Dec. 31, 2022	Oct. 31, 2021	Sep. 30, 2022	Dec. 31, 2023	Dec. 31, 2022
License, Collaboration and Manufacturing Agreements [Line Items]
License and collaboration revenue					$ 687	$ 63,573
Deferred revenue, December 31, 2022	$ 115,395	$ 85,000			115,395	85,000
Less: deferred revenue - current portion	77,833				77,833
Deferred revenue - long-term, December 31, 2023	37,562	77,000			37,562	77,000
Deferred revenue, revenue recognized					5,000
Bayer Manufacturing Agreement
License, Collaboration and Manufacturing Agreements [Line Items]
License and collaboration revenue				$ 61,800	0
Deferred revenue, December 31, 2022	0	0			0	0
Receivable for early contract				4,200
Hcrx Agreement [Member]
License, Collaboration and Manufacturing Agreements [Line Items]
Proceeds from sale of future royalties, gross					$ 31,000	31,000
Minimum Cash Repayment					185.00%
Maximum Cash Repayment					250.00%
Bayer Agreements
License, Collaboration and Manufacturing Agreements [Line Items]
License and collaboration revenue						61,800
Pierre Fabre Commercialization Agreement
License, Collaboration and Manufacturing Agreements [Line Items]
Upfront cash payment received	$ 20,000		$ 45,000
Royalty eligible to receive term after first commercial sale	12 years		12 years
License and collaboration revenue						1,800
Development or sales-based milestone payments earned or received		40,000		$ 30,000
Determined upfront payment constituted entire consideration included in transaction price			$ 45,000
Milestone payments		$ 40,000				40,000
Pierre Fabre Commercialization Agreement | Maximum
License, Collaboration and Manufacturing Agreements [Line Items]
Aggregate milestone payments entitle to receive upon achieving certain regulatory and commercial milestones	$ 620,000		$ 308,000		$ 620,000
A&R Commercialization Agreement [Member]
License, Collaboration and Manufacturing Agreements [Line Items]
License and collaboration revenue					700	$ 1,800
Additional Upfront Payment Included inTransaction Price	$ 20,000				$ 20,000