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Restructuring - Summary of future termination benefit payments (Details) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2023
Sep. 30, 2022
Sep. 30, 2023
Sep. 30, 2022
Restructuring Cost and Reserve [Line Items]        
Total restructuring charges $ 0 $ 5,890 $ 45 $ 5,890
General and administrative        
Restructuring Cost and Reserve [Line Items]        
Total restructuring charges 0 3,180 45 3,180
Research and development        
Restructuring Cost and Reserve [Line Items]        
Total restructuring charges $ 0 $ 2,710 $ 0 $ 2,710