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Condensed Consolidated Statements of Operations and Comprehensive Loss (Unaudited) - USD ($)
shares in Thousands, $ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2023
Sep. 30, 2022
Sep. 30, 2023
Sep. 30, 2022
Income Statement [Abstract]        
Commercialization revenue $ 2,020 $ 0 $ 3,697 $ 0
License and collaboration revenue 118 4,459 624 63,352
Total revenue 2,138 4,459 4,321 63,352
Costs and operating expenses:        
Cost of commercialization revenue 2,615 0 5,726 0
Research and development expenses 56,888 70,157 175,185 210,018
General and administrative expenses 12,247 18,924 39,454 58,308
Total costs and operating expenses 71,750 89,081 220,365 268,326
Loss from operations (69,612) (84,622) (216,044) (204,974)
Other income (expense), net:        
Interest income 1,218 973 4,715 1,904
Interest expense (1,395) (123) (4,109) (256)
Gain on sale of ATOM Facility 0 0 0 50,237
Other income (expense), net (27) (309) (234) (631)
Total other income (expense), net 204 541 372 51,254
Loss before provision for (benefit from) income taxes (69,816) (84,081) (215,672) (153,720)
Provision for (benefit from) income taxes (19) 10 4 10
Net loss (69,797) (84,091) (215,676) (153,730)
Other comprehensive gain (loss):        
Unrealized gain (loss) on available-for-sale securities 362 (341) 1,496 (2,591)
Comprehensive loss $ (69,435) $ (84,432) $ (214,180) $ (156,321)
Basic loss per common share $ (0.66) $ (0.82) $ (2.05) $ (1.51)
Diluted loss per common share $ (0.66) $ (0.82) $ (2.05) $ (1.51)
Basic weighted-average shares outstanding 106,401 102,423 105,163 101,590
Diluted weighted-average shares outstanding 106,401 102,423 105,163 101,590