XML 48 R34.htm IDEA: XBRL DOCUMENT v3.22.4
Summary of Significant Accounting Policies - Additional Information (Detail)
$ in Thousands
1 Months Ended 12 Months Ended
Jan. 31, 2023
USD ($)
Dec. 31, 2022
USD ($)
Segment
Dec. 31, 2021
USD ($)
Dec. 31, 2020
USD ($)
Significant Accounting Policies [Line Items]        
Number of reportable segments | Segment   1    
Number of operating segments | Segment   1    
License and collaboration revenue   $ 63,573 $ 20,340 $ 0
Cash and cash equivalents maturity period   90 days    
Investment maturity period   90 days    
Impairment of long-lived assets   $ 0    
Expected dividend yield   0.00% 0.00% 0.00%
Defined contribution plan, plan name   401(k)    
Defined contribution plan, matching contribution percentage   50.00%    
Defined contribution plan, maximum percentage of an individual's eligible earnings   6.00%    
Defined contribution plan contributions by employer   $ 2,300 $ 2,600 $ 2,100
Minimum        
Significant Accounting Policies [Line Items]        
Property, plant and equipment, useful life   3 years    
Maximum        
Significant Accounting Policies [Line Items]        
Property, plant and equipment, useful life   5 years    
Bayer Agreements        
Significant Accounting Policies [Line Items]        
License and collaboration revenue   $ 61,800    
Pierre Fabre Commercialization Agreement        
Significant Accounting Policies [Line Items]        
License and collaboration revenue   $ 1,800    
Pierre Fabre Commercialization Agreement | Subsequent Event [Member]        
Significant Accounting Policies [Line Items]        
Payment received upon achievement of certain milestones $ 40,000