Equity, January 2021 Offerings (Details) - USD ($)					12 Months Ended
	Feb. 24, 2021	Feb. 23, 2021	Jan. 06, 2021	Jul. 16, 2020	Dec. 31, 2021	Dec. 31, 2020
January 2021 Offerings [Abstract]
Warrants issued to purchase shares of common stock (in shares)				137,746
Exercise price of warrants (in dollars per share)				$ 9.60
Percentage of placement agent fee paid				1.00%
Common stock shares authorized (in shares)	250,000,000	150,000,000			25,000,000	25,000,000
Accounting for the January 2021 Offerings [Abstract]
Deemed dividends on preferred stock issuances				$ 8,200,000	$ 4,507,125	$ 8,155,212
Series B Most Favored Nations Exchanges Offerings [Abstract]
Conversion of stock amount converted					$ 0	$ 0
Series C Preferred Stock Converted into Common Stock [Member]
January 2021 Offerings [Abstract]
Shares issued upon conversion (in shares)		1,316,662
Conversion price (in dollars per share)		$ 7.70
Series B Most Favored Nations Exchanges Offerings [Abstract]
Number of shares converted (in shares)					33,097.10
Conversion of stock amount converted					$ 24,700,000
Conversion of stock, shares issued (in shares)	3,344.63				3,125,460
Series B Preferred Stock Converted into Common Stock [Member]
January 2021 Offerings [Abstract]
Shares issued upon conversion (in shares)	334.46
Conversion price (in dollars per share)						$ 7.70
Series B Most Favored Nations Exchanges Offerings [Abstract]
Number of shares converted (in shares)	33,699				258.08	254.54
Conversion of stock amount converted	$ 2,000				$ 2,000,000.0
Conversion of stock, shares issued (in shares)					258,278	256,581
Series B Preferred Stock Exchanged for Common Shares [Member]
January 2021 Offerings [Abstract]
Shares issued, price per share (in dollars per share)					$ 3.40
Series B Most Favored Nations Exchanges Offerings [Abstract]
Number of shares converted (in shares)					13.80
Conversion of stock amount converted					$ 100,000
Conversion of stock, shares issued (in shares)					33,500
Common Stock [Member]
Series B Most Favored Nations Exchanges Offerings [Abstract]
Conversion of stock amount converted					$ 26	$ 26
Conversion of stock, shares issued (in shares)					258,278	256,581
Common Stock [Member] | Series C Preferred Stock Converted into Common Stock [Member]
January 2021 Offerings [Abstract]
Shares issued upon conversion (in shares)	33,446
Series B Preferred Stock [Member]
January 2021 Offerings [Abstract]
Shares agreed to sell in offering (in shares)				2,912.583005
Shares issued, price per share (in dollars per share)				$ 7,700.00
Conversion price (in dollars per share)					$ 7.70
Warrants issued to purchase shares of common stock (in shares)				468,499
Series B Most Favored Nations Exchanges Offerings [Abstract]
Number of shares converted (in shares)					1,877.64
Conversion of stock amount converted					$ 14,500,000
Conversion of stock, shares issued (in shares)					1,839.76
Series B Preferred Stock [Member] | Series B Preferred Stock Converted into Common Stock [Member]
January 2021 Offerings [Abstract]
Shares issued upon conversion (in shares)					1,921,645
Series C Preferred Stock [Member]
January 2021 Offerings [Abstract]
Shares issued upon conversion (in shares)					19,140.14
Warrants issued to purchase shares of common stock (in shares)					1,913,971
Gross proceeds from issuance of equity			$ 4,600,000
Accounting for the January 2021 Offerings [Abstract]
Deemed dividends on preferred stock issuances			$ 4,500,000		$ 21,000,000.0
Series B Most Favored Nations Exchanges Offerings [Abstract]
Conversion of stock, shares issued (in shares)		13,166.62			19,216.45
January 2021 Investor Warrants [Member]
January 2021 Offerings [Abstract]
Warrants issued to purchase shares of common stock (in shares)			1,066,666
Exercise price of warrants (in dollars per share)			$ 8.00
Warrants expiration date					Jul. 06, 2026
Gross proceeds from issuance of equity			$ 3,400,000
January 2021 Investor Warrants [Member] | Common Stock [Member]
January 2021 Offerings [Abstract]
Warrants issued to purchase shares of common stock (in shares)					1,921,645
January 2021 Placement Agent Warrants [Member]
January 2021 Offerings [Abstract]
Shares issued, price per share (in dollars per share)			$ 7.50
Warrants issued to purchase shares of common stock (in shares)			74,667
Exercise price of warrants (in dollars per share)			$ 9.375
Warrants expiration date					Jul. 06, 2026
Percentage of common stock issued in offering			7.00%
Reimbursement of non-accountable expenses			$ 35,000
Reimbursement of legal fees and expenses			125,000
Reimbursement of clearing fees			$ 12,900
January 2021 Placement Agent Warrants [Member] | Series C Preferred Stock [Member]
January 2021 Offerings [Abstract]
Percentage of effective purchase price per share of preferred stock			125.00%
January 2021 Offerings [Member]
January 2021 Offerings [Abstract]
Gross proceeds from issuance of equity			$ 8,000,000.0
Net proceeds from issuance of equity			$ 6,800,000
Percentage of placement agent fee paid			8.00%
Percentage of management fee paid			1.00%
Placement agent fee and management fee			$ 700,000
Accounting for the January 2021 Offerings [Abstract]
Offering costs			$ 1,200,000
January 2021 Registered Direct Offering [Member] | Series C Preferred Stock [Member]
January 2021 Offerings [Abstract]
Shares agreed to sell in offering (in shares)						5,333.333
Shares issued, price per share (in dollars per share)						$ 750.00
Shares issued upon conversion (in shares)						533,333
Conversion price (in dollars per share)						$ 7.50
January 2021 Private Placement [Member]
January 2021 Offerings [Abstract]
Common stock shares authorized (in shares)	25,000,000	15,000,000
January 2021 Private Placement [Member] | Series C Preferred Stock [Member]
January 2021 Offerings [Abstract]
Shares agreed to sell in offering (in shares)			5,333.3333