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Stock Options (Tables)
 12 Months Ended
Dec. 31, 2021
Stock Options [Abstract]  
Stock Options-pricing Model with Weighted Average Assumptions
The fair values were estimated on the grant dates using the Black-Scholes option-pricing model with the following weighted-average assumptions: 

 
December 31,
  
   
2021
    
2020
  
Contractual term (in years)
    
9-10
      
5 - 10
  
Volatility
    
83.8 - 90.6
%
    
81.0 - 85.0
%
Risk-free interest rate
    
0.93 - 1.69
%
    
0.62 - 1.88
%
Dividend yield
    
-
 %    
-
 %
Stock Option Activity
During the years ended December 31, 2021 and 2020, stock option activity under the 2014 Plan and 2020 Plan was as follows:

   
Number
of Shares
    
Average
Exercise
Price
    
Remaining
Contract
Life (Years)
    
Intrinsic
Value
  
Stock options outstanding on January 1, 2021
    
407,028
    
$
13.80
      
7.94
    
$
-
  
Granted during the period
    
175,246
    
$
8.61
      
8.32
    
$
-
  
Canceled during the period
    
(143,082
)
  
$
10.47
      
2.87
    
$
-
  
Stock options outstanding on December 31, 2021
    
439,192
    
$
11.58
      
7.28
    
$
-
  
Exercisable on December 31, 2021
    
281,418
    
$
13.41
      
6.55
    
$
-
  
                                 
Non-vested stock options outstanding on January 1, 2021
    
274,065
    
$
9.90
      
8.42
    
$
-
  
Granted during the period
    
175,246
    
$
8.61
      
8.32
    
$
-
  
Vested during the period
    
(186,862
)
  
$
10.41
      
-
    
$
-
  
Canceled during the period
    
(104,521
)
  
$
9.84
      
-
    
$
-
  
Non-vested stock options outstanding on December 31, 2021
    
157,928
    
$
8.32
      
8.58
    
$
-
  

   
Number
of Shares
    
Average
Exercise
Price
    
Remaining
Contract
Life (Years)
    
Intrinsic
Value
  
Stock options outstanding on January 1, 2020
    
167,750
    
$
21.70
      
5.37
    
$
-
  
Granted during the period
    
288,001
    
$
8.90
      
9.06
    
$
-
  
Canceled during the period
    
(48,723
)
  
$
27.70
       -    
$
-
  
Stock options outstanding on December 31, 2020
    
407,028
    
$
13.80
      
7.94
    
$
-
  
Exercisable on December 31, 2020
    
132,963
    
$
17.80
      
6.67
    
$
-
  
                                 
Non-vested stock options outstanding on January 1, 2020
    
88,350
    
$
13.30
      
6.26
    
$
-
  
Granted during the period
    
288,001
    
$
8.90
      
9.06
    
$
-
  
Vested during the period
    
(84,063
)
  
$
9.80
       -    
$
-
  
Canceled during the period
    
(18,223
)
  
$
17.50
       -    
$
-
  
Non-vested stock options outstanding on December 31, 2020
    
274,065
    
$
9.90
      
8.42
    
$
-