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Warrants (Tables)
12 Months Ended
Dec. 31, 2021
Warrants [Abstract]  
Warrant Transactions
Warrant transactions for the years ending December 31, 2021 and 2020 were as follows:

   
Warrants
   
Exercise
Price Per
Share
   
Weighted
Average
Price
 
                   
Warrants outstanding and exercisable on January 1, 2020
   
537,829
   
$
10.70 - 73.70
   
$
25.30
 
Granted during the period
   
1,987,968
   
$
8.50 - 14.20
   
$
8.80
 
Expired during the period
   
(8,075
)
 
$
32.50 - 73.70
   
$
41.10
 
Exercised during the period
   
-
     
-
     
-
 
Warrants outstanding and exercisable on December 31, 2020
   
2,517,722
   
$
8.50 - 73.70
   
$
12.20
 
                         
Warrants outstanding and exercisable on January 1, 2021
   
2,517,722
   
$
8.50 - 73.70
   
$
12.20
 
Granted during the period
   
4,095,602
   
$
0.01 - 16.90
     
7.46
 
Expired during the period
   
(133,346
)
 
$
0.01 - 14.20
   
$
33.98
 
Exercised during the period
   
(952,588
)
 
$
15.00 - 73.70
   
$
5.32
 
Warrants outstanding and exercisable on December 31, 2021
   
5,527,390
   
$
0.80 – 6.60
   
$
9.49
 
Warrants Exercisable Price Range
Warrants exercisable at December 31, 2021 were as follows:
 
   
Exercise Price
   
Number of Shares Under Warrants
   
Weighted Average
Remaining
Contract Life in
Years
 
Weighted
Average
Exercise
Price
 
 
$
0.00 - 9.99
     
4,582,860
     
4.12
 
 
   
$
10.00 - 19.99
     
803,631
     
3.54
   
 
 
$
20.00 - 29.99
     
32,003
     
1.56
 
 
   
$
30.00 - 39.99
     
43,463
     
0.57
   
 
 
$
40.00 - 49.99
     
16,425
     
0.27
 
 
   
$
50.00 - 59.99
     
48,208
     
0.40
   
 
 
$
60.00 - 69.99
     
800
     
0.42
 
 
Totals
           
5,527,390
     
3.95
 
 $      9.49
Weighted Average Assumptions The grant date fair values were calculated using the Black-Scholes model with the following weighted average assumptions:
 
   
December 31,
 
   
2021
   
2020
 
Expected life (in years)
   
4.38
     
5
 
Volatility
   
83.8- 90.8
%
   
81.0- 85.0
%
Risk-free interest rate
   
0.36- 0.90
%
   
0.28- 1.67
%
Dividend yield
   
-
%
   
-
%