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Intangible Assets and Goodwill
12 Months Ended
Dec. 31, 2021
Intangible Assets and Goodwill [Abstract]  
Intangible Assets and Goodwill
Note 7 - Intangible Assets and Goodwill
 
Patents
 
Pursuant to the Mayoly APA entered into in March 2019 (see Note 15), in which the Company purchased all remaining rights, title and interest in and to adrulipase from Mayoly, the Company recorded Patents in the amount of approximately $3.8 million as follows:
 
Common stock issued at signing to Mayoly
 
$
1,740,959
 
Due to Mayoly at December 31, 2019
   
449,280
 
Due to Mayoly at December 31, 2020
   
393,120
 
Assumed Mayoly liabilities and forgiveness of Mayoly debt
   
1,219,386
 
 
 
$
3,802,745
 

Intangible assets are as follows:

   
December 31,
 
   
2021
   
2020
 
Patents
 
$
3,802,745
   
$
3,802,745
 
Less accumulated amortization
   
(1,450,757
)
   
(923,209
)
Intangible asset impairment
    (2,351,988 )     -  
Patents, net
 
$
-
   
$
2,879,536
 

Amortization expense was approximately $528,000 for both years ended December 31, 2021, and 2020, respectively.
 
During the year ended December 31, 2021, the Company recorded impairment charges of approximately $2.4 million related to patents that the Company determined were no longer sufficient for the commercialization of adrulipase.
 
Goodwill is as follows:

   
Goodwill
 
Balance on January 1, 2020
  $
1,886,686
 
Foreign currency translation
   
167,362
 
Balance on December 31, 2020
   
2,054,048
 
Foreign currency translation
   
(142,343
)
Balance on December 31, 2021
  $
1,911,705