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Consolidated Statements of Cash Flows - USD ($)
12 Months Ended
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Operating activities      
Net loss $ (13,227,642) $ (10,382,059) $ (9,258,647)
Adjustment to reconcile net loss to net cash used in operating activities:      
Depreciation and amortization 1,285,902 843,387 184,946
Share-based compensation 872,177 263,396 122,134
Gain on disposal of equipment (12,133) (13,233) (941)
Loss on asset held for sale 149,800 0 0
Impairment loss 103,116 0 0
Other non-cash charges 0 (1,364) 0
Changes in operating assets and liabilities:      
Other receivables 65,002 56,212 (11,440)
Inventory (1,154,222) 93,956 (169,991)
Prepaid expenses and other assets 59,942 289,868 (592,602)
Accounts payable, accrued liabilities and other liabilities 609,311 (966,928) 625,763
Net cash used in operating activities (11,248,747) (9,816,765) (9,100,778)
Investing activities      
Purchase of property, plant and equipment (2,316,809) (4,009,736) (18,893,264)
Deposits on equipment purchases (160,675) (95,001) (153,663)
Proceeds from sale of equipment 15,848 23,233 941
Net cash used in investing activities (2,461,636) (4,081,504) (19,045,986)
Financing activities      
Proceeds from issuance of debt 900,767 771,858 256,807
Repayment of term debt (85,802) (55,615) (35,812)
Proceeds from the issuance of common stock and warrants, net 12,395,348 10,616,046 24,989,257
Proceeds from exercise of stock options and warrants, net 272,417 5,116,533 27,502
Net cash provided by financing activities 13,482,730 16,448,822 25,237,754
Effect of exchange rate changes on cash and cash equivalents 23,840 (54,279) 80,018
Net change in cash and cash equivalents (203,813) 2,496,274 (2,828,992)
Cash and cash equivalents at beginning of period 3,002,557 506,283 3,335,275
Cash and cash equivalents at the end of period 2,798,744 3,002,557 506,283
Supplemental disclosure of cash flow information and non-cash transactions:      
Interest paid in cash 62,988 22,257 21,537
Property and equipment included in accounts payable and accrued liabilities 210,270 193,378 1,036,240
Acquisition of equipment under debt arrangement $ 0 $ 74,068 $ 0