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Consolidated Statements of Changes in Stockholders' Equity (Deficit) - USD ($)
Total
Common Stock
Additional paid-in capital
Accumulated other comprehensive loss
Accumulated deficit
Beginning balance (in shares) at Dec. 31, 2016   6,463,936      
Beginning balance at Dec. 31, 2016 $ 2,028,055 $ 6,464 $ 101,581,724 $ (286,272) $ (99,273,861)
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Net loss (9,258,647)       (9,258,647)
Other comprehensive income (loss) 72,388     72,388  
Issuance of common stock, net of expenses (in shares)   2,421,073      
Issuance of common stock, net of expenses 24,989,257 $ 2,421 24,986,836    
Exercise of options for common stock (in shares)   8,334      
Exercise of options for common stock 27,502 $ 8 27,494    
Share based compensation (in shares)   1,751      
Share based compensation 122,134 $ 2 122,132    
Ending balance (in shares) at Dec. 31, 2017   8,895,094      
Ending balance at Dec. 31, 2017 17,980,689 $ 8,895 126,718,186 (213,884) (108,532,508)
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Net loss (10,382,059)       (10,382,059)
Other comprehensive income (loss) (360,302)     (360,302)  
Issuance of common stock, net of expenses (in shares)   3,692,307      
Issuance of common stock, net of expenses 10,616,046 $ 3,692 10,612,354    
Exercise of warrants for common stock, net of expenses (in shares)   2,500,285      
Exercise of warrants for common stock, net of expenses 5,116,533 $ 2,501 5,114,032    
Share based compensation (in shares)   11,151      
Share based compensation 263,396 $ 11 263,385    
Ending balance (in shares) at Dec. 31, 2018   15,098,837      
Ending balance at Dec. 31, 2018 23,234,303 $ 15,099 142,707,957 (574,186) (118,914,567)
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Net loss (13,227,642)       (13,227,642)
Other comprehensive income (loss) 214,026     214,026  
Issuance of common stock, net of expenses (in shares)   6,246,360      
Issuance of common stock, net of expenses $ 12,395,348 $ 6,246 12,389,102    
Exercise of warrants for common stock, net of expenses (in shares) 83,564 83,564      
Exercise of warrants for common stock, net of expenses $ 272,417 $ 84 272,333    
Share based compensation (in shares)   206,604      
Share based compensation 872,177 $ 206 871,971    
Ending balance (in shares) at Dec. 31, 2019   21,635,365      
Ending balance at Dec. 31, 2019 $ 23,760,629 $ 21,635 $ 156,241,363 $ (360,160) $ (132,142,209)