ESPERION THERAPEUTICS INC NE COMMON 29664W105 21369 464549 SH DFND 1 0 0 464549 ESPERION THERAPEUTICS INC NE COMMON 29664W105 5 100 SH DFND 0 0 100 INSEEGO CORP NOTE 5.500% 6/1 45782BAA2 12097 13700000 PRN DFND 0 0 13700000 INSEEGO CORP COMMON 45782B104 78017 18799229 SH DFND 0 0 18799229 MACROGENICS INC. COMMON 556099109 48 3815 SH DFND 1 0 0 3815 MEDICINES CO COMMON 584688105 13464 703440 SH DFND 1 0 0 703440 MEDICINES CO COMMON 584688105 58859 3075202 SH DFND 2 0 0 3075202 MEDICINES CO COMMON 584688105 2 100 SH DFND 0 0 100 MIRATI THERAPEUTICS INC COMMON 60468T105 133028 3135966 SH DFND 1 0 0 3135966 SOLID BIOSCIENCES INC. COMMON 83422E105 308 11488 SH DFND 1 0 0 11488