ESPERION THERAPEUTICS INC NE COMMON 29664W105 53244 1200000 SH DFND 1 0 0 1200000 ESPERION THERAPEUTICS INC NE COMMON 29664W105 4 100 SH DFND 0 0 100 INSEEGO CORP NOTE 5.500% 6/1 45782BAA2 11222 13700000 PRN DFND 0 0 13700000 INSEEGO CORP COMMON 45782B104 34829 9046500 SH DFND 0 0 9046500 MACROGENICS INC. COMMON 556099109 14253 664785 SH DFND 1 0 0 664785 MEDICINES CO COMMON 584688105 21040 703440 SH DFND 1 0 0 703440 MEDICINES CO COMMON 584688105 91979 3075202 SH DFND 2 0 0 3075202 MEDICINES CO COMMON 584688105 3 100 SH DFND 0 0 100 MIRATI THERAPEUTICS INC COMMON 60468T105 147704 3135966 SH DFND 1 0 0 3135966 SOLID BIOSCIENCES INC. COMMON 83422E105 542 11488 SH DFND 1 0 0 11488