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  <schemaVersion>X0202</schemaVersion>
  <headerData>
    <submissionType>13F-HR</submissionType>
    <filerInfo>
      <liveTestFlag>LIVE</liveTestFlag>
      <flags>
        <confirmingCopyFlag>false</confirmingCopyFlag>
        <returnCopyFlag>false</returnCopyFlag>
        <overrideInternetFlag>false</overrideInternetFlag>
      </flags>
      <filer>
        <credentials>
          <cik>0001603466</cik>
          <ccc>XXXXXXXX</ccc>
        </credentials>
      </filer>
      <periodOfReport>12-31-2025</periodOfReport>
    </filerInfo>
  </headerData>
  <formData>
    <coverPage>
      <reportCalendarOrQuarter>12-31-2025</reportCalendarOrQuarter>
      <isAmendment>false</isAmendment>
      <filingManager>
        <name>Point72 Asset Management, L.P.</name>
        <address>
          <ns1:street1>72 CUMMINGS POINT ROAD</ns1:street1>
          <ns1:city>STAMFORD</ns1:city>
          <ns1:stateOrCountry>CT</ns1:stateOrCountry>
          <ns1:zipCode>06902</ns1:zipCode>
        </address>
      </filingManager>
      <reportType>13F HOLDINGS REPORT</reportType>
      <form13FFileNumber>028-16256</form13FFileNumber>
      <crdNumber>000283077</crdNumber>
      <secFileNumber>801-107348</secFileNumber>
      <provideInfoForInstruction5>Y</provideInfoForInstruction5>
      <additionalInformation>This Form 13F-HR is filed by Point72 Asset Management, L.P. ("Point72").   Certain other managers affiliated with Point72 and listed as relying advisers on the Form ADV of Point72 that are not separately listed in this report also have investment discretion (through sub-advisory relationships) over certain positions (or portions of positions) listed in this report. Point72 is under common control with CPV Partners, LLC (Form 13F File Number 028-19347) ("CPV"), 72 Investment Holdings, LLC (Form 13F File Number 028-20409), and Point72 Private Investments, LLC (Form 13F File Number 028-23092) each of which separately file Form 13F-HR. * Positions that are exempt from reporting under Special Instruction 10 to the Form 13F are excluded from this report. However, positions that would not be exempt when aggregated with positions of the same security over which each of the foregoing managers have investment discretion are listed herein.</additionalInformation>
    </coverPage>
    <signatureBlock>
      <name>Jason M. Colombo</name>
      <title>Authorized Person</title>
      <phone>203-890-2000</phone>
      <signature>/s/ Jason M. Colombo</signature>
      <city>Stamford</city>
      <stateOrCountry>CT</stateOrCountry>
      <signatureDate>02-17-2026</signatureDate>
    </signatureBlock>
    <summaryPage>
      <otherIncludedManagersCount>0</otherIncludedManagersCount>
      <tableEntryTotal>3862</tableEntryTotal>
      <tableValueTotal>89421368731</tableValueTotal>
    </summaryPage>
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