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    <periodOfReport>2024-06-10</periodOfReport>

    <issuer>
        <issuerCik>0001603454</issuerCik>
        <issuerName>Celcuity Inc.</issuerName>
        <issuerTradingSymbol>CELC</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001213869</rptOwnerCik>
            <rptOwnerName>NIGON RICHARD</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>16305 36TH AVENUE NORTH</rptOwnerStreet1>
            <rptOwnerStreet2>SUITE 100</rptOwnerStreet2>
            <rptOwnerCity>MINNEAPOLIS</rptOwnerCity>
            <rptOwnerState>MN</rptOwnerState>
            <rptOwnerZipCode>55446</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
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    <footnotes>
        <footnote id="F1">Currently exercisable.</footnote>
        <footnote id="F2">This Option will vest and become exercisable on April 30, 2025 or if earlier, the date of the Company's 2025 Annual Meeting of Stockholders.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ Eric O. Madson as Attorney-in-Fact for Richard Nigon pursuant to Power of Attorney previously filed.</signatureName>
        <signatureDate>2024-06-12</signatureDate>
    </ownerSignature>
</ownershipDocument>
