X0306 4 2021-03-02 0000318154 AMGEN INC AMGN 0001602343 Piacquad David ONE AMGEN CENTER DRIVE THOUSAND OAKS CA 91320-1799 1 SVP, Business Development Common Stock 2021-03-02 4 A 0 2648 0 A 45504 D These shares include the following Restricted Stock Units (RSUs) granted under the Company's equity plans: 335 RSUs which vest on 5/1/2021; 642 RSUs which vest in installments of 316 on 4/27/2021 and 326 on 4/27/2022; 1,691 RSUs which will vest in two installments of 558 on 5/3/2021 and 5/3/2022 and one installment of 575 on 5/3/2023; and 1,269 RSUs which vest in installments of 418 on 5/5/2022, 419 on 5/5/2023 and 432 on 5/5/2024. Vested RSUs will be paid in shares of the Company's common stock on a one-to-one basis. These shares include 202 Dividend Equivalents (DEs) granted pursuant to the Amgen Inc. 2009 Amended and Restated Equity Incentive Plan and subject to a qualifying dividend reinvestment plan. DEs are credited on the reporting person's unvested RSUs and are paid out in shares of the Company's common stock on a one-to-one basis according to the vesting schedule, along with a cash payment for any remaining fractional amount. /s/ David A. Piacquad 2021-03-04