X0306 4 2023-01-25 0 0001680367 Shattuck Labs, Inc. STTK 0001601942 Schreiber Taylor C/O SHATTUCK LABS, INC. 500 W. 5TH STREET, SUITE 1200 AUSTIN TX 78701 1 1 0 0 Chief Executive Officer Stock Option (Right to Buy) 3.57 2023-01-25 4 A 0 165050 0.00 D 2033-01-25 Common Stock 165050 165050 D This option represents the right to purchase a total of 165,050 shares of the Issuer's common stock, and will vest upon the Issuer's common stock achieving specified share prices during the four years following the grant date, subject to the Reporting Person's continued service to the Issuer. /s/ Erin Ator Thomson, Attorney-in-Fact for Taylor Schreiber 2023-01-27