Accrued Expenses (Tables)

12 Months Ended

Dec. 31, 2017

Accrued Expenses/Trade and Other Payables [Abstract]

Components of accrued expenses

	December 31, 2017		December 31, 2016
Accrued research and development costs including milestone payments		4,060,048		4,307,089
Professional fees		227,363		316,470
Accrued vacation & overtime		69,455		115,749
Employee benefits incl. share based payments		217,649		138,960
Board of Directors fees		—		1,529
Other		108,198		26,945
Total accrued expenses		4,682,713		4,906,742