Supplemental disclosure of cash flow information
Supplemental Cash Flow Information [Abstract]
Affiliated holders, ownership percentage
Affiliated Holders, Ownership Percentage
Affiliated Holders, Ownership Percentage
Letter of credit
Letter of Credit [Member]
Vested (in shares)
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Vested in Period
Fair Value Hierarchy and NAV [Domain]
Fair Value Hierarchy and NAV [Domain]
Leasehold improvements
Leasehold Improvements [Member]
Net loss and comprehensive loss
Net loss
Net Income (Loss) Attributable to Parent
Entity Emerging Growth Company
Entity Emerging Growth Company
Accrued compensation
Employee-related Liabilities, Current
Income Statement Location [Axis]
Income Statement Location [Axis]
Property Subject to or Available for Operating Lease [Axis]
Property Subject to or Available for Operating Lease [Axis]
Statistical Measurement [Domain]
Statistical Measurement [Domain]
Accumulated Amortization
Finite-Lived Intangible Assets, Accumulated Amortization
Entity Address, Address Line One
Entity Address, Address Line One
Schedule of maturities of long-term debt
Schedule of Maturities of Long-term Debt [Table Text Block]
Share-based Payment Arrangement, Nonemployee
Share-based Payment Arrangement, Nonemployee [Member]
Forfeited (in shares)
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value
Undistributed earnings, basic
Undistributed Earnings, Basic
Entity Filer Category
Entity Filer Category
Options, cancelled in period (in shares)
Share-based Compensation Arrangement by Share-based Payment Award, Options, Forfeitures in Period
Convertible preferred stock, shares outstanding (in shares)
Temporary equity, shares outstanding at beginning of period (in shares)
Temporary equity, shares outstanding at end of period (in shares)
Preferred shares outstanding (in shares)
Temporary Equity, Shares Outstanding
Other non-current assets
Other Assets, Noncurrent
Schedule of Share-based Compensation Arrangements by Share-based Payment Award [Table]
Schedule of Share-based Compensation Arrangements by Share-based Payment Award [Table]
Expected dividend yield
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Dividend Rate
Number of shares available for grant (in shares)
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Available for Grant
Retirement Benefits [Abstract]
Net change in cash, cash equivalents and restricted cash
Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Period Increase (Decrease), Including Exchange Rate Effect
Expected volatility
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Volatility Rate
Common Stock, Number of Shares, Par Value and Other Disclosures [Abstract]
Common Stock, Number of Shares, Par Value and Other Disclosures [Abstract]
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation, Calculation [Roll Forward]
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation, Calculation [Roll Forward]
2023
Long-Term Debt, Maturity, Year Two
Stock-based compensation
APIC, Share-based Payment Arrangement, Increase for Cost Recognition
Net increase in fair value of warrants
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability, Gain (Loss) Included in Earnings
Options, exercised in period, intrinsic value
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercises in Period, Intrinsic Value
2021
Long-Term Debt, Maturity, Remainder of Fiscal Year
Document Fiscal Year Focus
Document Fiscal Year Focus
Subsequent Event Type [Domain]
Subsequent Event Type [Domain]
Lessee, Lease, Description [Line Items]
Lessee, Lease, Description [Line Items]
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Amortization expense
Amortization of Intangible Assets
Antidilutive securities excluded from computation of loss per share, amount (in shares)
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount
Research and development
Research and Development Expense [Member]
Sale of Stock [Axis]
Sale of Stock [Axis]
Liability Class [Axis]
Liability Class [Axis]
Subsequent Events [Abstract]
Stock split, conversion ratio
Stockholders' Equity Note, Stock Split, Conversion Ratio
Granted (in dollars per share)
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value
Series A-1
Convertible Series A-1 Preferred Stock [Member]
Convertible Series A-1 Preferred Stock
Schedule of indefinite-lived intangible assets
Schedule of Indefinite-Lived Intangible Assets [Table Text Block]
Award Type [Domain]
Award Type [Domain]
Notes payable, net of current portion
Notes Payable, Noncurrent
Credit Facility [Domain]
Credit Facility [Domain]
Assets
Assets [Abstract]
Related Party Transactions [Abstract]
2024
Long-Term Debt, Maturity, Year Three
Options, exercisable, number (in shares)
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Number
Granted (in shares)
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Grants in Period
Goodwill and Intangible Assets
Goodwill and Intangible Assets Disclosure [Text Block]
Options, outstanding, number (in shares)
Options, outstanding, number at beginning of period (in shares)
Options, outstanding, number at end of period (in shares)
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Number
Entity Address, City or Town
Entity Address, City or Town
Accrued development expenses
Accrued Development Costs, Current
Accrued Development Costs, Current
Research project, fees and milestones payments receivable for an option on a development candidate
Collaborative Agreement, Research Project, Maximum Fees And Milestones Payments Receivable For An Option On A Development Candidate
Collaborative Agreement, Research Project, Maximum Fees And Milestones Payments Receivable For An Option On A Development Candidate
Accumulated Deficit
Retained Earnings [Member]
IPO
IPO [Member]
Debt Instrument [Axis]
Debt Instrument [Axis]
Commitments and Contingencies
Commitments and Contingencies Disclosure [Text Block]
Conversion of preferred stock to common stock
Stock issued during the period, value of conversion of convertible securities
Stock Issued During Period, Value, Conversion of Convertible Securities
Komas
Komas [Member]
Komas
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table]
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table]
Related Party [Axis]
Related Party [Axis]
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items]
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items]
Accounts receivable
Increase (Decrease) in Accounts Receivable
Accrued property and equipment
Capital Expenditures Incurred but Not yet Paid
Schedule of temporary equity
Temporary Equity [Table Text Block]
Options, granted in period, fair value
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Fair Value
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Fair Value
Debt instrument, additional interest only period
Debt Instrument, Periodic Payments, Additional Interest Only Period
Debt Instrument, Periodic Payments, Additional Interest Only Period
Interest income
Investment Income, Nonoperating
Property, Plant and Equipment [Line Items]
Property, Plant and Equipment [Line Items]
Commitments and Contingencies Disclosure [Abstract]
The National Institute Of Health
The National Institute Of Health [Member]
The National Institute Of Health
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Table]
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Table]
Entity Interactive Data Current
Entity Interactive Data Current
Incentive from lessor
Incentive from Lessor
Share-based Payment Arrangement, Expensed and Capitalized, Amount [Line Items]
Share-based Payment Arrangement, Expensed and Capitalized, Amount [Line Items]
Net loss per share of Class A and B common stock, basic (in dollars per share)
Net loss per share, basic (in dollars per shares)
Earnings Per Share, Basic
Fair value of warrants at beginning of period
Fair value of warrants at end of period
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability Value
Beginning balance, outstanding (in shares)
Ending balance, outstanding (in shares)
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Nonvested, Number
Document Type
Document Type
2022
Long-Term Debt, Maturity, Year One
Warrants, grand date fair value (in dollars per share)
Class Of Warrant Or Right, Grant Date Fair Value
Class Of Warrant Or Right, Grant Date Fair Value
Convertible Preferred Stock
Temporary Equity [Text Block]
Temporary Equity
Employee benefit plan, employer expenses
Defined Contribution Plan, Cost
Accrued early discovery expenses
Accrued Early Discovery Expenses, Current
Accrued Early Discovery Expenses, Current
Fair Value Measurement [Domain]
Fair Value Measurement [Domain]
Entity Current Reporting Status
Entity Current Reporting Status
Schedule of Nonvested RSU Activity
Nonvested Restricted Stock Shares Activity [Table Text Block]
Other, net
Other Noncash Income (Expense)
Convertible preferred stock, par value (in dollars per share)
Temporary Equity, Par or Stated Value Per Share
Plan Name [Axis]
Plan Name [Axis]
Total liabilities
Long-term Debt
Total assets
Assets, Fair Value Disclosure
Level 1
Fair Value, Inputs, Level 1 [Member]
Cash flows from investing activities
Net Cash Provided by (Used in) Investing Activities [Abstract]
Goodwill impairment
Goodwill, Impairment Loss
Fair Value by Liability Class [Domain]
Fair Value by Liability Class [Domain]
Document Transition Report
Document Transition Report
Income Tax Disclosure [Abstract]
Restricted cash
Restricted Cash and Cash Equivalents, Fair Value Disclosure
Restricted Cash and Cash Equivalents, Fair Value Disclosure
IPO, expenses costs
Payments of Stock Issuance Expenses
Payments of Stock Issuance Expenses
Research project, fees and milestones payments receivable for an option on a lead series
Collaborative Agreement, Research Project, Maximum Fees And Milestones Payments Receivable For An Option On A Lead Series
Collaborative Agreement, Research Project, Maximum Fees And Milestones Payments Receivable For An Option On A Lead Series
Pacific Western Bank loan
Pacific Western Bank Loan [Member]
Pacific Western Bank Loan
Total liabilities, convertible preferred stock and stockholders’ equity (deficit)
Liabilities and Equity
Accrued other expenses
Other Accrued Liabilities, Current
Current portion of unearned revenue
Contract with Customer, Liability, Current
2025
Operating Leases, Future Minimum Payments, Due in Four Years
Current portion of lease incentive obligation
Lease Incentive, Payable, Current
Options, exercised in period, weighted average exercise price (in dollars per share)
Share-based Compensation Arrangements by Share-based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price
Restricted cash
Restricted Cash
Additional paid-in capital
Additional Paid in Capital
Lessee, Lease, Description [Table]
Lessee, Lease, Description [Table]
Interest rate increase in case of contract breach
Debt Instrument, Contract Breach, Interest Rate Increase
Debt Instrument, Contract Breach, Interest Rate Increase
Impairment of indefinite-lived intangible assets
Impairment of Intangible Assets, Indefinite-lived (Excluding Goodwill)
Liabilities, convertible preferred stock and stockholders’ equity (deficit)
Liabilities and Equity [Abstract]
Purchase period
Share Based Compensation Arrangement By Share-Based Payment Award, Purchase Period
Share Based Compensation Arrangement By Share-Based Payment Award, Purchase Period
Proceeds from initial public offering of common stock, net of issuance costs
Proceeds from Issuance Initial Public Offering
Accounts payable
Increase (Decrease) in Accounts Payable
Series C
Convertible Series C Preferred Stock [Member]
Convertible Series C Preferred Stock
Net Loss Per Share
Earnings Per Share [Text Block]
Operating expenses
Operating Expenses [Abstract]
Book values
Portion at Other than Fair Value Measurement [Member]
Stock option exercises and other
Stock Issued During Period, Value, Stock Options Exercised
Minimum
Minimum [Member]
2016 Equity incentive plan
2016 Equity Incentive Plan [Member]
2016 Equity Incentive Plan
Line of credit outstanding
Long-term Line of Credit
2023
Operating Leases, Future Minimum Payments, Due in Two Years
Supplemental Financial Information
Supplemental Balance Sheet And Income Statement Information [Text Block]
Supplemental Balance Sheet And Income Statement Information
Total liabilities
Financial and Nonfinancial Liabilities, Fair Value Disclosure
Net loss and comprehensive loss
Comprehensive Income (Loss), Net of Tax, Attributable to Noncontrolling Interest
Less: unamortized issuance costs
Debt Issuance Costs, Net
Class of Warrant or Right [Domain]
Class of Warrant or Right [Domain]
Trading Symbol
Trading Symbol
Fair Value Disclosure of Asset and Liability Not Measured at Fair Value
Fair Value Disclosure of Asset and Liability Not Measured at Fair Value [Table Text Block]
Current liabilities
Liabilities, Current [Abstract]
Loan to related party
Loans and Leases Receivable, Related Parties
2025
Long-Term Debt, Maturity, Year Four
Common stock issuance for initial public offering, net of issuance costs
Stock Issued During Period, Value, New Issues
General and administrative
General and Administrative Expense
Notes Payable
Debt Disclosure [Text Block]
Options, exercisable, weighted average exercise price (in dollars per share)
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Weighted Average Exercise Price
Line of credit
Line of Credit [Member]
Stock-Based Compensation
Share-based Payment Arrangement [Text Block]
Level 3
Fair Value, Inputs, Level 3 [Member]
Accounting Policies [Abstract]
Deferred issuance costs recorded in equity
Debt Issuance Costs Incurred During Noncash or Partial Noncash Transaction
Options, outstanding, weighted average remaining contractual life
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term
IPO, underwriting discounts and commissions
Payments of Stock Issuance Costs
Common stock issuance for initial public offering, net of issuance costs (in shares)
Stock Issued During Period, Shares, New Issues
Lease incentive obligation, net of current portion
Lease Incentive, Payable, Noncurrent
Lease Incentive, Payable, Noncurrent
Interest income and expense disclosure
Interest Income and Interest Expense Disclosure [Table Text Block]
Common stock (Class A and B), $0.00001 par value; 2,000,000,000 (Class A 1,989,032,117, Class B 10,967,883) and 188,400,000 shares authorized as of June 30, 2021 and December 31, 2020, respectively; 168,425,907 (Class A 158,958,024, Class B 9,467,883) and 22,314,685 shares issued and outstanding as of June 30, 2021 and December 31, 2020, respectively
Common Stock, Value, Issued
Other loss, net
Nonoperating Income (Expense)
Unvested stock options, unamortized stock-based compensation cost, weighted average period recognition
Share-based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition
Beginning balance, outstanding Weighted average grant date fair value (in dollars per share)
Ending balance, outstanding Weighted average grant date fair value (in dollars per share)
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value
Basis of presentation and emerging growth company
Basis of Accounting, Policy [Policy Text Block]
Performance shares
Performance Shares [Member]
Commitments and contingencies (Note 6)
Commitments and Contingencies
Subsequent Event [Table]
Subsequent Event [Table]
Non-refundable upfront payment received
Collaborative Agreement, Non-Refundable Upfront Payment Received
Collaborative Agreement, Non-Refundable Upfront Payment Received
Number of renewal options (in extension periods)
Lessee, Operating Lease, Number Of Renewal Options
Lessee, Operating Lease, Number Of Renewal Options
Restricted stock
Restricted Stock [Member]
Collaborative agreement, potential funding remaining
Collaborative Agreement, Potential Funding Remaining
Collaborative Agreement, Potential Funding Remaining
2024
Operating Leases, Future Minimum Payments, Due in Three Years
Payments of fees in connection with the midcap loan agreement
Payments of Debt Issuance Costs
Schedule of Share-based Payment Award, Stock Options, Valuation Assumptions
Schedule of Share-based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]
Fair Value Disclosure of Asset and Liability Not Measured at Fair Value [Table]
Fair Value Disclosure of Asset and Liability Not Measured at Fair Value [Table]
Antidilutive Securities, Name [Domain]
Antidilutive Securities, Name [Domain]
Document Period End Date
Document Period End Date
Schedule of Preferred Units [Table]
Schedule of Preferred Units [Table]
Debt instrument, periodic payment, principal
Debt Instrument, Periodic Payment, Principal
Conversion of preferred stock to common stock
Temporary Equity, Value, Conversion Of Convertible Securities
Temporary Equity, Value, Conversion Of Convertible Securities
Class of Stock [Axis]
Class of Stock [Axis]
Warrants issued (in shares)
Class Of Warrant Or Right, Issued
Class Of Warrant Or Right, Issued
Entity Registrant Name
Entity Registrant Name
Numerator:
Net Income (Loss) Available to Common Stockholders, Diluted [Abstract]
Collaborative Arrangement and Arrangement Other than Collaborative [Axis]
Collaborative Arrangement and Arrangement Other than Collaborative [Axis]
Warrants outstanding (in shares)
Class of Warrant or Right, Outstanding
IPO, net proceeds received
Sale of Stock, Consideration Received on Transaction
Convertible preferred stock (series A, A-1, B, C, and D), $0.00001 par value; 200,000,000 and 121,434,713 shares authorized as of June 30, 2021 and December 31, 2020, respectively; 0 and 112,088,065 shares issued and outstanding as of June 30, 2021 and December 31, 2020, respectively; Liquidation preference of $0 and $450,850 as of June 30, 2021 and December 31, 2020, respectively
Temporary equity, carrying amount attributable to parent at beginning of period
Temporary equity, carrying amount attributable to parent at end of period
Carrying Value
Temporary Equity, Carrying Amount, Attributable to Parent
Deferred rent
Deferred Rent Credit, Noncurrent
Accrued expenses and other liabilities
Accrued expenses and other liabilities
Accrued Liabilities, Current
Revenue
Revenue from grants
Revenue from Contract with Customer, Excluding Assessed Tax
Office equipment
Office Equipment [Member]
Stock options
Share-based Payment Arrangement, Option [Member]
Fair Value Hierarchy and NAV [Axis]
Fair Value Hierarchy and NAV [Axis]
Equity [Abstract]
Convertible notes payable
Convertible Notes Payable [Member]
Lease Arrangement Name [Domain]
Lease Arrangement Name [Domain]
Lease Arrangement Name [Domain]
Notes payable
Notes Payable, Other Payables [Member]
Common Stock (Class A and B)
Common Stock [Member]
Variable Rate [Axis]
Variable Rate [Axis]
Loss from operations
Operating Income (Loss)
Property, Plant and Equipment [Table]
Property, Plant and Equipment [Table]
Collaborative and Other Research and Development Contracts
Collaborative Arrangement Disclosure [Text Block]
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Stock-based compensation
Share-based Payment Arrangement, Noncash Expense
Variable Rate [Domain]
Variable Rate [Domain]
Additional Paid-in-Capital
Additional Paid-in Capital [Member]
Cash and cash equivalents
Cash and Cash Equivalents, at Carrying Value
Depreciation
Depreciation
Repayments of debt
Repayments of Debt
Long-term Debt, Type [Domain]
Long-term Debt, Type [Domain]
Change in fair value of derivate
Gain (Loss) on Derivative Instruments, Net, Pretax
Collaborative Arrangement and Arrangement Other than Collaborative [Domain]
Collaborative Arrangement and Arrangement Other than Collaborative [Domain]
Accrued development expense
Increase (Decrease) In Accrued Development Expense
Increase (Decrease) In Accrued Development Expense
Affiliated holders, potential ownership percentage when outstanding equity awards vest
Affiliated Holders, Potential Ownership Percentage When Outstanding Equity Awards Vest
Affiliated Holders, Potential Ownership Percentage When Outstanding Equity Awards Vest
Total liabilities
Long-term Debt, Fair Value
Purchases of property and equipment
Payments to Acquire Property, Plant, and Equipment
Series A
Convertible Series A Preferred Stock [Member]
Convertible Series A Preferred Stock
Maximum
Maximum [Member]
Share-based Payment Arrangement [Abstract]
Shares of common stock issuable upon conversion (in shares)
Temporary Equity, Shares Subscribed but Unissued
Total liabilities
Liabilities
Grants receivable
Grants Receivable
Award Type [Axis]
Award Type [Axis]
Options, grants in period, weighted average exercise price (in dollars per share)
Share-based Compensation Arrangements by Share-based Payment Award, Options, Grants in Period, Weighted Average Exercise Price
Cash flows from financing activities
Net Cash Provided by (Used in) Financing Activities [Abstract]
Options, outstanding, intrinsic value
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Intrinsic Value
Size of additional leased asset
Lessee, Operating Lease, Size Of Additional Leased Asset Available
Lessee, Operating Lease, Size Of Additional Leased Asset Available
Total stockholders’ equity (deficit)
Total stockholders’ equity (deficit) at beginning of period
Total stockholders’ equity (deficit) at end of period
Stockholders' Equity Attributable to Parent
Warrants Arrangements [Table]
Warrants Arrangements [Table]
Warrants Arrangements [Table]
Common stock, shares issued (in shares)
Common Stock, Shares, Issued
Recorded in equity upon exercise
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability, Settlements
Options, exercisable, intrinsic value
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Intrinsic Value
Interest expense, net
Interest Revenue (Expense), Net
Property Subject to or Available for Operating Lease [Domain]
Property Subject to or Available for Operating Lease [Domain]
Goodwill and Intangible Assets Disclosure [Abstract]
Thereafter
Operating Leases, Future Minimum Payments, Due Thereafter
Accrued expenses, deferred rent and other current liabilities
Increase (Decrease) in Other Accrued Liabilities
Stockholders’ equity (deficit)
Stockholders' Equity Attributable to Parent [Abstract]
Current portion of notes payable
Notes Payable, Current
Supplemental disclosure of non—cash investing and financing information
Noncash Investing and Financing Items [Abstract]
Measurement Frequency [Domain]
Measurement Frequency [Domain]
Debt instrument, face amount
Debt Instrument, Face Amount
Interest expense
Interest Expense
City Area Code
City Area Code
Accumulated deficit
Accumulated deficit
Retained Earnings (Accumulated Deficit)
Stock options and RSUs
Share-based Payment Arrangement [Member]
Lease term
Lessee, Operating Lease, Term of Contract
Stock options, expiration period
Share-based Compensation Arrangement by Share-based Payment Award, Expiration Period
RSUs
Restricted Stock Units (RSUs) [Member]
Conversion of preferred stock to common stock
Conversion of Stock, Amount Converted
Statement of Stockholders' Equity [Abstract]
Employee benefit plan, percentage of matching contribution
Defined Contribution Plan, Employer Matching Contribution, Percent of Match
Risk-free interest rate
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Risk Free Interest Rate
Options, outstanding, estimated fair value at grand date
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Estimated Fair Value At Grand Date
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Estimated Fair Value At Grant Date
Station 41 lease
Station 41 Lease [Member]
Station 41 Lease
Amendment Flag
Amendment Flag
Fair values
Estimate of Fair Value Measurement [Member]
Summary Of Changes In Company's Warrant Liability
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Table Text Block]
Series D
Convertible Series D Preferred Stock [Member]
Convertible Series D Preferred Stock
Indefinite-lived intangible asset
Indefinite-lived Intangible Assets (Excluding Goodwill)
Proceeds from exercise of stock options
Proceeds from Stock Options Exercised
Basis of Presentation
Basis of Presentation and Significant Accounting Policies [Text Block]
2017 Warrants
2017 Warrants [Member]
2017 Warrants
Income tax expense
Income Tax Expense (Benefit)
Options, cancelled in period, weighted average exercise price (in dollars per share)
Share-based Compensation Arrangements by Share-based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price
Midcap loan agreement, tranche 1
Midcap Loan Agreement, Term Loan Facility, Tranche One Member [Member]
Midcap Loan Agreement, Term Loan Facility, Tranche One Member
Accounts receivable
Accounts Receivable, after Allowance for Credit Loss, Current
Proceeds from issuance of long-term debt
Proceeds from Issuance of Long-term Debt
Pacific Western letter of credit
Pacific Western Letter Of Credit [Member]
Pacific Western Letter Of Credit
Equity Components [Axis]
Equity Components [Axis]
Fair Value Disclosures [Abstract]
Antidilutive Securities [Axis]
Antidilutive Securities [Axis]
Total current assets
Assets, Current
Number of projects that may be initiated (in projects)
Collaborative Agreement, Number Of Projects That May Be Initiated
Collaborative Agreement, Number Of Projects That May Be Initiated
Sale of Stock [Domain]
Sale of Stock [Domain]
Total minimum payments
Lessee, Operating Lease, Liability, to be Paid
Forfeited (in shares)
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Forfeited in Period
Schedule of Stock by Class [Table]
Schedule of Stock by Class [Table]
Entity File Number
Entity File Number
Preferred Units [Line Items]
Preferred Units [Line Items]
Statement of Financial Position [Abstract]
Unvested stock options, unamortized stock-based compensation cost
Share-based Payment Arrangement, Nonvested Award, Option, Cost Not yet Recognized, Amount
Current portion of notes payable
Long-term Debt, Current Maturities
Product and Service [Axis]
Product and Service [Axis]
Long-Lived Tangible Asset [Domain]
Long-Lived Tangible Asset [Domain]
Fair Value, by Balance Sheet Grouping [Table]
Fair Value, by Balance Sheet Grouping [Table]
Conversion of preferred stock to common stock (in shares)
Temporary Equity, Shares, Conversion Of Convertible Securities
Temporary Equity, Shares, Conversion Of Convertible Securities
Entity Incorporation, State or Country Code
Entity Incorporation, State or Country Code
Series A and Series B Warrants
Series A And Series B Warrants [Member]
Series A And Series B Warrants
Entity Small Business
Entity Small Business
Grantee Status [Axis]
Grantee Status [Axis]
Unrecognized compensation cost
Share-based Payment Arrangement, Nonvested Award, Excluding Option, Cost Not yet Recognized, Amount
Midcap loan agreement, tranche 2
Midcap Loan Agreement, Term Loan Facility, Tranche Two Member [Member]
Midcap Loan Agreement, Term Loan Facility, Tranche Two Member
Chief Executive Officer
Chief Executive Officer [Member]
Options granted in period, weighted average grant date fair value (in dollars per share)
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value
Equity Component [Domain]
Equity Component [Domain]
Shares issued during the period (in shares)
Share-based Compensation Arrangement by Share-based Payment Award, Shares Issued in Period
2018 Warrants
2018 Warrants [Member]
2018 Warrants
Statement [Line Items]
Statement [Line Items]
ESPP
2021 Employee Stock Purchase Plan [Member]
2021 Employee Stock Purchase Plan
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items]
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items]
Increase (Decrease) in Contract with Customer, Liability
Increase (Decrease) in Contract with Customer, Liability
Impairment of definite-lived intangible assets
Impairment of Intangible Assets, Finite-lived
Grantee Status [Domain]
Grantee Status [Domain]
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price [Abstract]
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price [Abstract]
Unvested warrants, unamortized stock-based compensation cost, weighted average period recognition
Class Of Warrant Or Right, Cost Not Yet Recognized, Period For Recognition
Class Of Warrant Or Right, Cost Not Yet Recognized, Period For Recognition
Counterparty Name [Domain]
Counterparty Name [Domain]
Intangible assets, gross
Intangible Assets, Gross (Excluding Goodwill)
Total Minimum Payments
Operating Leases, Future Minimum Payments Due
Debt Disclosure [Abstract]
Entity Address, State or Province
Entity Address, State or Province
Purchase price of common stock (as a percent)
Share-based Compensation Arrangement by Share-based Payment Award, Purchase Price of Common Stock, Percent
Level 2
Fair Value, Inputs, Level 2 [Member]
Long-Lived Tangible Asset [Axis]
Long-Lived Tangible Asset [Axis]
Document Information [Table]
Document Information [Table]
Unearned revenue, net of current portion
Contract with Customer, Liability, Noncurrent
2016 Warrants
2016 Warrants [Member]
2016 Warrants
2022
Operating Leases, Future Minimum Payments Due, Next Twelve Months
Fair Value Disclosure, Asset and Liability, Not Measured at Fair Value [Line Items]
Fair Value Disclosure, Asset and Liability, Not Measured at Fair Value [Line Items]
Temporary Equity [Abstract]
Temporary Equity [Abstract]
Employee Benefit Plans
Retirement Benefits [Text Block]
Schedule of Basic and Diluted Net Loss per Share
Schedule of Earnings Per Share, Basic and Diluted [Table Text Block]
Options, granted in period (in shares)
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross
Entity Shell Company
Entity Shell Company
Local Phone Number
Local Phone Number
Summary of Stock-based Compensation Expenses
Share-based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]
Total assets
Assets
Plan Name [Domain]
Plan Name [Domain]
Vote per share of common stock (in votes)
Common Stock, Vote Per Share
Common Stock, Vote Per Share
Common stock, shares authorized (in shares)
Common Stock, Shares Authorized
Cash paid for interest
Interest Paid, Excluding Capitalized Interest, Operating Activities
Research and development
Research and Development Expense
Product and Service [Domain]
Product and Service [Domain]
Debt Instrument, interest rate
Debt Instrument, Interest Rate, Stated Percentage
Schedule of Earnings Per Share, Basic, by Common Class, Including Two Class Method [Table]
Schedule of Earnings Per Share, Basic, by Common Class, Including Two Class Method [Table]
Operating lease, renewal term
Lessee, Operating Lease, Renewal Term
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Measurement Frequency [Axis]
Measurement Frequency [Axis]
Net cash used in operating activities
Net Cash Provided by (Used in) Operating Activities
Schedule of debt
Schedule of Debt [Table Text Block]
Schedule of Long-term Debt Instruments [Table]
Schedule of Long-term Debt Instruments [Table]
Entity Tax Identification Number
Entity Tax Identification Number
Subsequent Event [Line Items]
Subsequent Event [Line Items]
Christopher Gibson and his affiliates
Christopher Gibson And Affiliates [Member]
Christopher Gibson And Affiliates
Warrants, fair value
Class Of Warrant Or Right, Fair Value
Class Of Warrant Or Right, Fair Value
Construction in progress
Asset under Construction [Member]
Weighted average shares outstanding, basic (in shares)
Weighted average common shares outstanding, basic (in shares)
Weighted Average Number of Shares Outstanding, Basic
Net loss per share of Class A and B common stock, diluted (in dollars per share)
Net loss per share, diluted (in dollars per shares)
Earnings Per Share, Diluted
Operating revenue
License and Service [Member]
Price per share
Sale of Stock, Price Per Share
Subsequent Events
Subsequent Events [Text Block]
Intangible assets, net
Intangible Assets, Net (Excluding Goodwill)
Convertible preferred stock, shares authorized (in shares)
Preferred shares authorized (in shares)
Temporary Equity, Shares Authorized
Warrants Arrangements [Line Items]
Warrants Arrangements [Line Items]
Warrants Arrangements
Net cash provided by financing activities
Net Cash Provided by (Used in) Financing Activities
Denominator:
Weighted Average Number of Shares Outstanding, Diluted [Abstract]
Related Party Transaction [Line Items]
Related Party Transaction [Line Items]
Stock options, vesting period
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Period
Loans payable
Loans Payable [Member]
Conversion of preferred stock to common stock (in shares)
Shares issued in the period, upon conversion (in shares)
Stock Issued During Period, Shares, Conversion of Convertible Securities
Fair Value Measurements
Fair Value Disclosures [Text Block]
Midcap loan agreement
Midcap Loan Agreement [Member]
Midcap Loan Agreement
Accounts payable
Accounts Payable, Current
Depreciation and amortization
Depreciation, Depletion and Amortization
Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis
Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis [Table Text Block]
Unvested warrants, unamortized stock-based compensation cost
Class Of Warrant Or Right, Cost Not Yet Recognized, Amount
Class Of Warrant Or Right, Cost Not Yet Recognized, Amount
Proceeds from convertible notes
Proceeds from Convertible Debt
Convertible preferred stock
Convertible Preferred Stock [Member]
Common sock, shares outstanding (in shares)
Common stock, shares outstanding at beginning period (in shares)
Common stock, shares outstanding at end period (in shares)
Common Stock, Shares, Outstanding
2021
Operating Leases, Future Minimum Payments, Remainder of Fiscal Year
Increase (Decrease) in Temporary Equity [Roll Forward]
Increase (Decrease) in Temporary Equity [Roll Forward]
Revenue
Revenues [Abstract]
Class B
Common Class B [Member]
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding [Roll Forward]
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding [Roll Forward]
Key personnel incentive plan
Key Personnel Incentive Plan [Member]
Key Personnel Incentive Plan
Schedule of property and equipment
Property, Plant and Equipment [Table Text Block]
Income Statement Location [Domain]
Income Statement Location [Domain]
Debt instrument, term
Debt Instrument, Term
Lease incentive, payable
Lease Incentive, Payable
Convertible preferred stock, shares issued (in shares)
Preferred shares issued (in shares)
Temporary Equity, Shares Issued
Property and equipment, net
Property and equipment, net
Property, Plant and Equipment, Net
Total operating expenses
Operating Expenses
Station 41
Station 41 [Member]
Station 41
Share-based Payment Arrangement, Employee
Share-based Payment Arrangement, Employee [Member]
Convertible preferred stock, liquidation preference
Liquidation Preferences
Temporary Equity, Liquidation Preference
Share-based Payment Arrangement, Expensed and Capitalized, Amount [Table]
Share-based Payment Arrangement, Expensed and Capitalized, Amount [Table]
Debt Instrument [Line Items]
Debt Instrument [Line Items]
Repayment of long-term debt
Repayments of Long-term Debt
Per share data
Earnings Per Share [Abstract]
Collaborative arrangement
Collaborative Arrangement [Member]
Property and equipment, gross
Property, Plant and Equipment, Gross
Document Quarterly Report
Document Quarterly Report
Future Minimum Lease Payments
Schedule of Future Minimum Rental Payments for Operating Leases [Table Text Block]
Other assets
Increase (Decrease) in Other Operating Assets
Warrants, exercise price (in dollars per share)
Class of Warrant or Right, Exercise Price of Warrants or Rights
Warrants
Warrant [Member]
Options, outstanding, weighted average exercise price at beginning of period (in dollars per share)
Options, outstanding, weighted average exercise price at end of period (in dollars per share)
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price
Collaborative agreement, term
Collaborative Agreement, Term
Collaborative Agreement, Term
Entity Common Stock, Shares Outstanding
Entity Common Stock, Shares Outstanding
Warrants, vesting period
Warrants and Rights Outstanding, Term
Notes payable, net of current portion
Long-term Debt, Excluding Current Maturities
Schedule of Related Party Transactions, by Related Party [Table]
Schedule of Related Party Transactions, by Related Party [Table]
Share-based payment arrangement, expense
Share-based Payment Arrangement, Expense
Options, exercisable, weighted average remaining contractual life
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term
Intangible assets, net
Intangible Assets, Net (Including Goodwill)
Earnings Per Share, Basic, by Common Class, Including Two Class Method [Line Items]
Earnings Per Share, Basic, by Common Class, Including Two Class Method [Line Items]
Weighted-average grant date fair value
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value [Abstract]
Document Fiscal Period Focus
Document Fiscal Period Focus
Restricted cash
Restricted Cash, Current
Counterparty Name [Axis]
Counterparty Name [Axis]
Class of Warrant or Right [Axis]
Class of Warrant or Right [Axis]
Class A
Common Class A [Member]
Cash, cash equivalents and restricted cash, beginning of period
Cash, cash equivalents and restricted cash, end of period
Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents
Collaborative agreement, potential funding
Collaborative Agreement, Potential Funding
Collaborative Agreement, Potential Funding
IPO, number of shares issued
Sale of Stock, Number of Shares Issued in Transaction
Common stock, par value (in dollars per share)
Common Stock, Par or Stated Value Per Share
Statement of Comprehensive Income [Abstract]
Current assets
Assets, Current [Abstract]
Gross carrying amount
Finite-Lived Intangible Assets, Gross
Common stock, capital shares reserved for future issuance (in shares)
Common Stock, Capital Shares Reserved for Future Issuance
Entity Central Index Key
Entity Central Index Key
Schedule of finite-lived intangible assets
Schedule of Finite-Lived Intangible Assets [Table Text Block]
London Interbank Offered Rate (LIBOR)
London Interbank Offered Rate (LIBOR) [Member]
Property and equipment additions
Property, Plant and Equipment, Additions
Security Exchange Name
Security Exchange Name
Cash and equivalents
Cash and Cash Equivalents, Fair Value Disclosure
Schedule of accrued expenses and other liabilities
Schedule of Accounts Payable and Accrued Liabilities [Table Text Block]
Stock option exercises and other (in shares)
Options, exercised in period (in shares)
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercises in Period
Weighted average shares outstanding, diluted (in shares)
Weighted average common shares outstanding, diluted (in shares)
Weighted Average Number of Shares Outstanding, Diluted
Warrant liability
Warrants and Rights Outstanding
Fair Value, Recurring
Fair Value, Recurring [Member]
Proceeds from note receivable
Proceeds from Collection of Notes Receivable
Income Taxes
Income Tax Disclosure [Text Block]
Related Party [Domain]
Related Party [Domain]
Long-term Debt, Type [Axis]
Long-term Debt, Type [Axis]
Current Fiscal Year End Date
Current Fiscal Year End Date
Schedule of Share-based Payment Arrangement, Option, Activity
Share-based Payment Arrangement, Option, Activity [Table Text Block]
Debt instrument, basis spread on variable rate
Debt Instrument, Basis Spread on Variable Rate
Common Stock
Stockholders' Equity Note Disclosure [Text Block]
Measurement Basis [Axis]
Measurement Basis [Axis]
Schedule of Antidilutive Securities Excluded from Computation of Net Loss Per Share
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
Statement of Cash Flows [Abstract]
Class of Stock [Line Items]
Class of Stock [Line Items]
Credit Facility [Axis]
Credit Facility [Axis]
Net cash used in investing activities
Net Cash Provided by (Used in) Investing Activities
Portion at Fair Value Measurement
Portion at Fair Value Measurement [Member]
Changes in operating assets and liabilities:
Increase (Decrease) in Operating Capital [Abstract]
Less: Accumulated depreciation
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment
Cash flows from operating activities
Net Cash Provided by (Used in) Operating Activities [Abstract]
Vested (in dollars per share)
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Vested in Period, Weighted Average Grant Date Fair Value
General and administrative
General and Administrative Expense [Member]
Expected term (in years)
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Term
Total current liabilities
Liabilities, Current
ESPP
Employee Stock [Member]
Class of Stock [Domain]
Class of Stock [Domain]
Maximum borrowing capacity
Line of Credit Facility, Maximum Borrowing Capacity
Revenue from contract with customer
Revenue from Contract with Customer, Including Assessed Tax
Employee benefit plan, employer matching contribution, percentage of employees' gross pay
Defined Contribution Plan, Employer Matching Contribution, Percent of Employees' Gross Pay
Entity Address, Postal Zip Code
Entity Address, Postal Zip Code
Lab equipment
Laboratory Equipment [Member]
Laboratory Equipment
Warrants Issued In January 2020
Warrants Issued In January 2020 [Member]
Warrants Issued In January 2020
Document Information [Line Items]
Document Information [Line Items]
Debt instrument, number of periodic payments
Debt Instrument, Number Of Periodic Payments
Debt Instrument, Number Of Periodic Payments
Debt Instrument, Name [Domain]
Debt Instrument, Name [Domain]
Title of 12(b) Security
Title of 12(b) Security
Statement [Table]
Statement [Table]
Other current assets
Other Assets, Current
Stock units
Share-based Compensation Arrangement by Share-based Payment Award, Non-Option Equity Instruments, Outstanding [Roll Forward]
Collaborative Arrangement and Arrangement Other than Collaborative [Table]
Collaborative Arrangement and Arrangement Other than Collaborative [Table]
Recent accounting pronouncements
New Accounting Pronouncements, Policy [Policy Text Block]
Unrecognized compensation cost
Share-based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount
Milpitas
Milpitas [Member]
Milpitas
Statistical Measurement [Axis]
Statistical Measurement [Axis]
Subsequent Event
Subsequent Event [Member]
Cover [Abstract]
Net carrying amount
Finite-Lived Intangible Assets, Net
Goodwill
Goodwill
2021 Equity Incentive Plan
2021 Equity Incentive Plan [Member]
2021 Equity Incentive Plan
Lease Arrangement Name [Axis]
Lease Arrangement Name [Axis]
Lease Arrangement Name
Bayer AG
Bayer AG [Member]
Bayer AG
Description of the Business
Nature of Operations [Text Block]
Adjustments to reconcile net loss to net cash used in operating activities:
Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract]
Grant revenue
Grant [Member]
Subsequent Event Type [Axis]
Subsequent Event Type [Axis]
Supplemental Financial Information [Abstract]
Supplemental Financial Information
Related Party Transactions
Related Party Transactions Disclosure [Text Block]
Rent expense
Operating Leases, Rent Expense
Undistributed earnings, diluted
Undistributed Earnings, Diluted
Thereafter
Long-Term Debt, Maturity, After Year Four
Long-Term Debt, Maturity, After Year Four
Employee benefit plan, percentage of maximum annual contributions per employee
Defined Contribution Plan, Maximum Annual Contributions Per Employee, Percent
Schedule of Share-based Payment, Award, ESPP, Valuation Assumptions
Schedule of Share-based Payment Award, Employee Stock Purchase Plan, Valuation Assumptions [Table Text Block]
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Series B
Convertible Series B Preferred Stock [Member]
Convertible Series B Preferred Stock