The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

OMB APPROVAL
OMB Number:3235-0006
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COLUMN 1COLUMN 2COLUMN 3COLUMN 4COLUMN 5COLUMN 6COLUMN 7COLUMN 8
VALUESHRS ORSH/PUT/INVESTMENTOTHERVOTING AUTHORITY
NAME OF ISSUERTITLE OF CLASSCUSIP(x$1000)PRN AMTPRNCALLDISCRETIONMANAGERSOLESHAREDNONE
ADAMAS PHARMACEUTICALS INCCOM00548A10618,5093,856,000SH DFND13,856,00000
ADOBE SYSTEMS INCORPORATEDCOM00724F10125,67054,000SH DFND154,00000
ADVANCE AUTO PARTS INCCOM00751Y10650,179273,469SH DFND1273,46900
ADVANTAGE SOLUTIONS INCCOM CL A00791N10210,629900,000SH DFND1900,00000
ALIBABA GROUP HLDG LTDSPONSORED ADS01609W10234,916154,000SH DFND1154,00000
ALKERMES PLCSHSG0176710565,8283,524,000SH DFND13,524,00000
ALPHATEC HLDGS INCCOM NEW02081G20110,042636,000SH DFND1636,00000
ALTIMMUNE INCCOM NEW02155H2007,574536,000SH DFND1536,00000
AMAZON COM INCCOM02313510677,35225,000SH DFND125,00000
AMERICAN EAGLE OUTFITTERS INCOM02553E10611,345387,995SH DFND1387,99500
AMRYT PHARMA PLCSPONSORED ADS03217L1062,786200,000SH DFND1200,00000
ANAPLAN INCCOM03272L1087,108132,000SH DFND1132,00000
ANHEUSER BUSCH INBEV SA/NVSPONSORED ADR03524A10843,995700,000SH DFND1700,00000
ARGENX SESPONSORED ADR04016X10141,309150,000SH DFND1150,00000
ASSEMBLY BIOSCIENCES INCCOM04539610810,2862,236,000SH DFND12,236,00000
AUDDIA INC*W EXP 10/17/20205072K1152130,400SH DFND130,40000
AVANTOR INCCOM05352A10018,399636,000SH DFND1636,00000
AXONICS MODULATION TECHNOLOGCOM05465P10125,034418,000SH DFND1418,00000
AYTU BIOPHARMA INCCOM NEW05475487410,2021,342,378SH DFND11,342,37800
AZURRX BIOPHARMA INCCOM05502L1058059,863SH DFND159,86300
B & G FOODS INC NEWCOM05508R1068,945288,000SH DFND1288,00000
BIO RAD LABS INCCL A09057220721,70438,000SH DFND138,00000
BIOGEN INCCOM09062X10380,568288,000SH DFND1288,00000
BIOHAVEN PHARMACTL HLDG CO LCOMG1119610568,3501,000,000SH DFND11,000,00000
BIONTECH SESPONSORED ADS09075V10230,136276,000SH DFND1276,00000
BLUEBIRD BIO INCCOM09609G10059,2151,964,000SH DFND11,964,00000
BRIACELL THERAPEUTICS CORP*W EXP 02/24/20210778Y112450420,536SH DFND1420,53600
BRISTOL-MYERS SQUIBB COCOM11012210894,6951,500,000SH DFND11,500,00000
CAMPBELL SOUP COCOM13442910946,449924,000SH DFND1924,00000
CATALYST PHARMACEUTICALS INCCOM14888U10146,10010,000,000SH DFND110,000,00000
CENTRAL GARDEN & PET COCL A NON-VTG15352720541,097792,000SH DFND1792,00000
CERECOR INCCOM15671L10998,55632,634,285SH DFND132,634,28500
CLOROX CO DELCOM18905410948,220250,000SH DFND1250,00000
COCA COLA COCOM19121610048,282916,000SH DFND1916,00000
COCA-COLA FEMSA SAB DE CVSPONSORD ADR REP19124110820,143436,000SH DFND1436,00000
COLGATE PALMOLIVE COCOM19416210318,604236,000SH DFND1236,00000
CRISPR THERAPEUTICS AGNAMEN AKTH1718210819,009156,000SH DFND1156,00000
CUENTAS INC*W EXP 99/99/9992297941104650,000SH DFND150,00000
DEXCOM INCCOM25213110729,47082,000SH DFND182,00000
DYNATRACE INCCOM NEW2681501097,236150,000SH DFND1150,00000
EAGLE PHARMACEUTICALS INCCOM2697961088,014192,000SH DFND1192,00000
ENANTA PHARMACEUTICALS INCCOM29251M10681,2791,648,000SH DFND11,648,00000
ENERGIZER HLDGS INC NEWCOM29272W10949,7381,048,000SH DFND11,048,00000
EXELA TECHNOLOGIES INCCOM NEW30162V4093,9641,818,182SH DFND11,818,18200
EYEGATE PHARMACEUTICALS INCCOM NEW30233M50316,6663,346,601SH DFND13,346,60100
FIVE BELOW INCCOM33829M10112,74566,800SH DFND166,80000
FUEL TECH INCCOM3595231072,669850,000SH DFND1850,00000
GAP INCCOM36476010815,355515,617SH DFND1515,61700
GOLD ROYALTY CORP*W EXP 99/99/99938071H114470448,000SH DFND1448,00000
HOSTESS BRANDS INCCL A44109J10618,3271,278,000SH DFND11,278,00000
HOTH THERAPEUTICS INCCOM44148G1054,4722,270,000SH DFND12,270,00000
ILLUMINA INCCOM45232710918,43548,000SH DFND148,00000
INCYTE CORPCOM45337C10283,8711,032,000SH DFND11,032,00000
INMED PHARMACEUTICALS INCCOM NEW457637502776235,000SH DFND1235,00000
ISHARES TRRUSSELL 2000 ETF464287655441,8802,000,000SHPutDFND12,000,00000
LAMB WESTON HLDGS INCCOM51327210421,539278,000SH DFND1278,00000
LANTHEUS HLDGS INCCOM51654410357,6992,700,000SH DFND12,700,00000
LEXARIA BIOSCIENCE CORP*W EXP 01/11/20252886N117865361,905SH DFND1361,90500
LULULEMON ATHLETICA INCCOM55002110910,23633,373SH DFND133,37300
MADRIGAL PHARMACEUTICALS INCCOM55886810540,940350,000SH DFND1350,00000
MEDIGUS LTD*W EXP 07/23/20258471G1281,1061,285,715SH DFND11,285,71500
MEDTRONIC PLCSHSG5960L10363,318536,000SH DFND1536,00000
MICROSOFT CORPCOM59491810425,463108,000SH DFND1108,00000
MINERVA NEUROSCIENCES INCCOM6033801062,663912,000SH DFND1912,00000
MIRATI THERAPEUTICS INCCOM60468T10591,817536,000SH DFND1536,00000
MONDELEZ INTL INCCL A60920710531,372536,000SH DFND1536,00000
NATERA INCCOM63230710425,182248,000SH DFND1248,00000
NIKE INCCL B65410610342,856322,491SH DFND1322,49100
NLS PHARMACEUTICS LTD*W EXP 09/25/202H57830111475500,000SH DFND1500,00000
NUVASIVE INCCOM67070410526,224400,000SH DFND1400,00000
OBALON THERAPEUTICS INCCOM NEW67424L2093,1021,100,000SH DFND11,100,00000
ORTHO CLINICAL DIAGNOSTICS HORD SHSG6829J10742,3722,196,000SH DFND12,196,00000
PAINREFORM LTDSHSM777981023,710839,346SH DFND1839,34600
PFIZER INCCOM71708110343,4761,200,000SH DFND11,200,00000
POOL CORPCOM73278L10512,73136,875SH DFND136,87500
POST HLDGS INCCOM73744610419,875188,000SH DFND1188,00000
POTBELLY CORPCOM73754Y1002,406407,099SH DFND1407,09900
PREDICTIVE ONCOLOGY INCCOM NEW74039M2002,4822,051,284SH DFND12,051,28400
PROGENITY INCCOM74319F10712,4832,622,377SH DFND12,622,37700
PTC THERAPEUTICS INCCOM69366J20066,1011,396,000SH DFND11,396,00000
RALPH LAUREN CORPCL A75121210135,780290,517SH DFND1290,51700
REGENERON PHARMACEUTICALSCOM75886F10782,800175,000SH DFND1175,00000
REWALK ROBOTICS LTDSHSM8216Q2004,6251,911,264SH DFND11,911,26400
REZOLUTE INCCOM NEW76200L3092,033288,000SH DFND1288,00000
SI BONE INCCOM82570410911,579364,000SH DFND1364,00000
SIENTRA INCCOM82621J1055,774792,000SH DFND1792,00000
SILK RD MED INCCOM82710M1007,598150,000SH DFND1150,00000
SIYATA MOBILE INC*W EXP 09/24/20283013Q152755150,000SH DFND1150,00000
SPDR S&P 500 ETF TRTR UNIT78462F103792,6602,000,000SHPutDFND12,000,00000
SPECTRUM PHARMACEUTICALS INCCOM84763A10834,88210,700,000SH DFND110,700,00000
SUPERNUS PHARMACEUTICALS INCCOM86845910889,3263,412,000SH DFND13,412,00000
TANDEM DIABETES CARE INCCOM NEW8753722038,825100,000SH DFND1100,00000
TELA BIO INCCOM8723811083,725250,000SH DFND1250,00000
TENAX THERAPEUTICS INCCOM NEW88032L2093,8382,019,995SH DFND12,019,99500
THERMO FISHER SCIENTIFIC INCCOM88355610226,47058,000SH DFND158,00000
TJX COS INC NEWCOM87254010974,6251,128,122SH DFND11,128,12200
TRACTOR SUPPLY COCOM89235610623,505132,737SH DFND1132,73700
TRAVERE THERAPEUTICS INCCOM89422G10758,8292,356,000SH DFND12,356,00000
TRIPADVISOR INCCOM8969452018,606160,000SH DFND1160,00000
UBER TECHNOLOGIES INCCOM90353T10019,624360,000SH DFND1360,00000
UNDER ARMOUR INCCL A90431110712,562566,881SH DFND1566,88100
UNITEDHEALTH GROUP INCCOM91324P10250,602136,000SH DFND1136,00000
VANDA PHARMACEUTICALS INCCOM92165910857,0163,796,000SH DFND13,796,00000
VERTEX PHARMACEUTICALS INCCOM92532F10084,237392,000SH DFND1392,00000
VIACOMCBS INCCL B92556H20628,142624,000SH DFND1624,00000
VOYAGER THERAPEUTICS INCCOM92915B10617,5023,716,000SH DFND13,716,00000
WALMART INCCOM93114210357,357422,268SH DFND1422,26800
WHOLE EARTH BRANDS INCCOM CL A96684W10015,6481,200,000SH DFND11,200,00000
WORKDAY INCCL A98138H1018,69535,000SH DFND135,00000
WYNN RESORTS LTDCOM9831341078,02464,000SH DFND164,00000
ZYMEWORKS INCCOM98985W10252,1071,650,000SH DFND11,650,00000