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Share-Based Compensation (Tables)
12 Months Ended
Dec. 31, 2021
Share-based Payment Arrangement [Abstract]  
Schedule of fair value measurement of equity-settled share options
  

Year ended
December 31,

 
   2021   2020 
         
Dividend yield   0%    0% 
Expected volatility of the share prices   65%    74%-79% 
Risk-free interest rate   1.4%-1.5%   0.6%-1.38% 
Expected term (in years)   8    8 

 

Schedule of stock option plans
  

Amount

of

options

  

Weighted

average

exercise

price

  

Weighted average remaining contractual term

(in years)

  

Aggregate

intrinsic value

 
                 
Balance as of December 31, 2020   3,892,714   $   5.15    6.65   $608,179 
                     
Granted   1,318,351    7.33    
-
    
-
 
Exercised   (438,759)   1.43    
-
    
-
 
Forfeited   (217,325)   7.20    
-
    
-
 
Expired   (143,557)   7.08    
-
    
-
 
                     
Balance as of December 31, 2021   4,411,424    6.01    8.19    92,507 
                     
Exercisable as of December 31, 2021   2,171,616   $5.57    7.11   $92,507 

 

Schedule of outstanding and exercisable option granted
Exercise price 

Options outstanding as of

December 31,
2021

  

Weighted average remaining

contractual term
(years)

  

Options exercisable as of December 31,

2021

  

Weighted average remaining

contractual term
(years)

 
                 
$ 0.25-3.80   435,346    9.18    123,494    5.82 
$ 4.15- 4.95   2,331,999    7.67    1,578,326    7.09 
$ 5.21-7.56   546,150    8.62    210,074    7.41 
$ 8.00-11.01   1,097,929    8.70    259,722    7.58 
                     
    4,411,424         2,171,616      

 

Schedule of of restricted shares activity
  

Amount

of

restricted shares

  

Weighted

average

grant date fair value

 
         
Unvested as of December 31, 2020   
-
   $
-
 
           
Granted   549,427    5.61 
Vested   
-
      
Forfeited   (17,950)   9.51 
           
Unvested as of December 31, 2021   531,477   $5.48 

 

Schedule of share-based compensation expense
   Year ended
December 31,
 
   2021   2020 
   (in thousands) 
Research and development expenses, net  $1,384   $1,099 
Commercial expenses   947    376 
General and administrative expenses   1,902    1,893 
Total share-based compensation  $4,233   $3,368