Condensed Consolidated Statements of Operations and Comprehensive Loss - USD ($) shares in Thousands, $ in Thousands	3 Months Ended
	Mar. 31, 2022	Mar. 31, 2021
Net revenue:
Total revenues	$ 21,625	$ 914
Operating expenses
Cost of sales	256	48
Selling, general and administrative	45,197	39,805
Research and development	12,620	9,833
Other expense, net	1,434	1,771
Total cost of sales and operating expenses	59,507	51,457
Loss from operations	(37,882)	(50,543)
Interest income	262	172
Net loss before income taxes	(37,620)	(50,371)
Income tax expense	10	8
Net loss	(37,630)	(50,379)
Other comprehensive loss:
Unrealized (loss) gain on available-for-sale securities, net of tax of nil	(766)	6
Comprehensive loss	$ (38,396)	$ (50,373)
Basic loss per share (expressed in $ per share)	$ (0.27)	$ (0.40)
Diluted loss per share (expressed in $ per share)	$ (0.27)	$ (0.40)
Weighted-average common shares outstanding used in computation of basic loss per share	141,675	127,401
Weighted-average common shares outstanding used in computation of diluted loss per share	141,675	127,401
Product revenue, net
Net revenue:
Total revenues	$ 21,492	$ 884
License and collaboration revenue
Net revenue:
Total revenues	$ 133	$ 30